In 2014, more than 93,000 people in the United States died from Alzheimer’s disease, according to the Centers for Disease Control and Prevention. The complex nature of Alzheimer’s makes it difficult to understand and predict, until it’s too late. Boston University professor and neuropsychologist Rhoda Au is trying to change that. Through the use...
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Discovery of novel autophagy regulators for treatment of neurodegenerative diseases
Synthesised curcumin analog C1 specifically binds to TFEB and promotes its nuclear translocation, and then activates autophagy and lysosome biogenesis to degrade alpha-synuclein. A research team led by Professor Li Min, Director of the Teaching and Research Division (CMTR), and Director of the Mr and Mrs Ko Chi Ming Centre for Parkinson’s Disease Research...
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Game therapy: serious video games can help children with cerebral palsy
Cerebral palsy (CP) is the most common childhood physical disability, affecting more than 34,000 Australians, and more than 17 million people worldwide. The condition results when there is an injury to the developing brain that goes on to affect a child’s movement and posture, but can also include the senses (vision, hearing, touch) and cognition (thinking). On...
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A novel principle to mobilize neurons for brain repair
Restorative neuroscience, the study to identify means to replace damaged neurons and recover permanently lost mental or physical abilities, is a rapidly advancing scientific field considering our progressively aging society. Redirecting immature neurons that reside in specific brain areas towards the sites of brain damage is an appealing strategy for the therapy of acute brain...
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Calcium imbalance within brain cells may trigger Alzheimer's disease
New research investigates the role of calcium production in Alzheimer’s disease. The neurodegenerative process may be caused by a calcium imbalance within the brain cell. New research suggests that a calcium processing dysfunction in the neurons’ mitochondria may drive Alzheimer’s disease. Mitochondria – sometimes referred to as the “powerhouse of the cell” – are small...
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Teens with PTSD, conduct disorder have difficulty recognizing facial expressions
Adolescents with posttraumatic stress disorder (PTSD) symptoms are more likely to misidentify sad and angry faces as fearful, while teens with symptoms of conduct disorder tend to interpret sad faces as angry, finds a study by NYU’s Steinhardt School of Culture, Education, and Human Development. “Our findings suggest that exposure to stress and trauma can...
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Scientists develop AI-based method to diagnose Alzheimer's or Parkinson's
Alzheimer’s disease, which currently affects more than 40 million people, is the most common neurodegenerative disease in elder people. Alzheimer’s disease, which currently affects more than 40 million people, is the most common neurodegenerative disease in elderly people. Early diagnosis is crucial both to treat the disease and to help the development of new...
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New test may quickly identify mild traumatic brain injury with underlying brain damage
A new test using peripheral vision reaction time could lead to earlier diagnosis and more effective treatment of mild traumatic brain injury, often referred to as a concussion, according to Peter J. Bergold, PhD, professor of physiology and pharmacology at SUNY Downstate Medical Center and corresponding author of a study newly published online by the...
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Stem Cell Transplants May Help Some With Multiple Sclerosis
Please note: This article was published more than one year ago. The facts and conclusions presented may have since changed and may no longer be accurate. And “More information” links may no longer work. Questions about personal health should always be referred to a physician or other health care professional. By Steven Reinberg HealthDay Reporter MONDAY,...
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Risky treatment can stop multiple sclerosis for years
A multiple sclerosis treatment being tested in patients can stop the disease for at least five years, say doctors. The risky therapy involves wiping out the person’s immune system with strong cancer drugs and then rebooting it with a stem cell transplant. Doctors say only some patients will be suitable to try it, particularly...