A new therapy called Juluca became the first two-drug treatment for HIV to get the FDA’s approval on Tuesday Juluca uses two active ingredients previously approved by the FDA to keep HIV viral loads at an undetectable level The new drug is part of a wave of innovative therapies attempting to make HIV treatment regimens...
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Over-the-counter supplement found on the High Street reduces breast cancer aggressiveness by up to 80%, breakthrough study finds
NAC, approved for colds, lowers levels of cancer aggressiveness marker MCT4 MCT4 is reduced by 80%, while the aggressive marker Ki67 decreases by 25% Drug contains antioxidants that make tumors release nutrients, stopping growth Low-toxicity treatment as its acceptable side effects have been shown in colds Researchers from the University of Salford analysed 12 breast cancer...
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Scientists reveal new avenue for drug treatment in neuropathic pain
New research from King’s College London has revealed a previously undiscovered mechanism of cellular communication, between neurons and immune cells, in neuropathic pain. The authors, who published their findings today in Nature Communications, identified a new method of treating neuropathic pain in mice, which could be more safe and effective than current treatments comprising of opioids...
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New meningitis vaccine could prevent 91% of strains, CDC discovers
Tests of a recently-developed meningitis B vaccine reveal that it can prevent nine of its 10 strains Researchers anticipate the shot could prevent 91 percent of strains that affect children in the US It targets the form of meningitis that has historically been the hardest to prevent The vaccine was approved for use on people ages...
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Team develops neuro test that distinguishes demyelinating diseases from multiple sclerosis
Mayo Clinic has launched a first-in-the-U.S. clinical test that will help patients who recently have been diagnosed with an inflammatory demyelinating disease (IDD) but may be unsure of the exact disorder. Neurologic-related diseases commonly affect the brain, optic nerves and the spinal cord, and this new test can distinguish other IDDs such as neuromyelitis optica,...
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How a simple urine test can now help doctors spot signs of prostate cancer with 98 per cent accuracy
Scientists claim that the test could prevent 41 per cent of unnecessary biopsies Symptoms of prostate cancer only tend to arise when tumour has grown large Men become eligible for the test if they have been identified as being at risk It is the most common form of cancer found in men in Britain, with...
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Second ‘don’t eat me’ signal found on cancer cells
Cancer cells. A second biological pathway that signals immune cells not to engulf and kill cancer cells has been identified by researchers at the Stanford University School of Medicine. An antibody that blocks the “don’t eat me” signal has shown promise as a cancer treatment in animal models and is currently in clinical trials. Combining...
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Researchers uncover link between immune function and osteoarthritic pain and progression
The immune system plays a pivotal role in the amount of pain and disease progression experienced by patients with osteoarthritis (OA), McMaster University researchers have found. This discovery could lead to new strategies for improving joint pain management and immune function in older adults with arthritis. The study, published in the medical journal Osteoarthritis and Cartilage,...
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Preventing HIV at the initial stages of infection
HIV infecting a human cell. In a project funded by the Austrian Science Fund FWF, Doris Wilflingseder investigates the initial stages of HIV infection, a period when the immune system might still stop the virus. “HIV has been intensively investigated in research labs all over the world for more than 30 years,” says Doris Wilflingseder,...
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New strategy for multiple myeloma immunotherapy
Fig.1.MMG49 CAR T cells target the activated conformation of integrin b7 expressed on MM cells. In recent decades monoclonal antibody-based treatment of cancer has been established as one of the most successful therapeutic strategies for both solid tumors and blood cancers. Monoclonal antibodies (mAb), as the name implies, are antibodies that are made by...