Alzheimer’s disease has a range of risk factors, but one of the clearest connections is the gene apoE4. Now, researchers at the Gladstone Institutes have peered closer at the protein encoded by this gene and uncovered how it affects the brain, how it increases the risks of Alzheimer’s and most importantly, how the damage can be reversed....
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There’s a better way to screen for cervical cancer
A new study in the Journal of the National Cancer Institute, published by Oxford University Press, indicates that high-quality cervical cancer screening can be done effectively using a completely automated approach. The researchers involved in the study indicate that automated technology could increase cervical screening coverage in underserved regions. Cervical cancer is caused by persistent infection...
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Severity of menopause symptoms could help predict heart disease
New study evaluates the effect of menopause and depression on vascular function THE NORTH AMERICAN MENOPAUSE SOCIETY (NAMS) CLEVELAND, Ohio (April 11, 2018)–Heart disease remains the leading cause of death in women. A study of 138 menopausal women examined the association of mood, symptoms, and quality of life measures with the key markers of vascular...
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Simultaneous chemo and immunotherapy may be better for some with metastatic bladder cancer
THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE (New York, NY- April 11, 2018) –Researchers from Mount Sinai and Sema4, a health information company and Mount Sinai venture, have discovered that giving metastatic bladder cancer patients simultaneous chemotherapy and immunotherapy is safe and that patients whose tumors have certain genetic mutations may respond...
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Blood test may predict future risk of cardiovascular events
Study of 27,000 women finds that branched-chain amino acid levels in the bloodstream are as predictive of heart disease as LDL cholesterol, other risk factors BRIGHAM AND WOMEN’S HOSPITAL Despite heart disease and type 2 diabetes being among the leading causes of death in the U.S., the mechanisms leading to and linking these two diseases...
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Study confirms link between traumatic brain injury and dementia
One of the largest studies of its kind, 2.8 million people, finds that TBIs’ number and severity heighten risk. UNIVERSITY OF WASHINGTON HEALTH SCIENCES/UW MEDICINE The risk of dementia, including Alzheimer’s, was significantly higher in people who had experienced a traumatic brain injury (TBI) than with people who had no history of TBI, according to...
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Research suggests alternative treatment for beta blocker intolerant heart attack patients
NEW YORK INSTITUTE OF TECHNOLOGY Beta blockers have become a prescription drug staple for recovering heart attack patients. However, these blood pressure-reducing medications cannot be tolerated by many patients who are at higher risk for developing cardiovascular disease, including those with chronic obstructive pulmonary disease (COPD) and asthma, the elderly, and diabetics. As seen in...
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Three things doctors say should be part of your weight loss efforts
A woman exercising on a stationary bike. Exercise is an important component of weight loss, most experts agree. Imagine that you are running a company, but you cannot get to your goal because all of your good workers keep quitting. For 30 years, your response to this problem has been to criticize the workers and...
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Researchers identify peptide produced during cartilage deterioration as a potential source of osteoarthritis pain
Credit: Rush University Medical Center Osteoarthritis is one of the most common causes of chronic pain in the world. More than 30 million people in the United States alone suffer from osteoarthritis, or OA, which can affect any moveable joint of the body, including the knees, hips and hands. OA normally manifests itself as a...
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Scientists test potential new way to treat anemia
Treatment of anemia caused by chronic kidney disease or other diseases often requires repeated—and costly—injections or infusions of an artificial form of the hormone erythropoietin (EPO), which stimulates the production of red blood cells. Now a Vanderbilt-led research team has shown they can reverse anemia in mice by injecting a kind of white blood cell called a...