Belly fat, even in people who are not otherwise overweight, is bad for the heart, according to results from the Mayo Clinic presented today at EuroPrevent 2018, a European Society of Cardiology congress. “See your doctor if your waist is bigger than your hips,” said study author Dr Jose Medina-Inojosa, from the division of Preventive...
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Unexpected memory retrieval mechanism found in landmark study
A landmark study exploring a little-researched area of the hippocampus made an unexpected discovery about how memory is retrieved. The scientists found, surprisingly, that memory retrieval and memory formation depend on very distinct mechanisms. Research on memory formation and memory retrieval is abundant and ongoing, as there is still so much we are yet to...
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Long-term diabetes complication: Liver inflammation raises cholesterol levels
Red/orange areas indicate precursors of atherosclerotic plaques called fatty streaks. Inflammatory processes in the liver lead to elevated cholesterol levels in people with diabetes, thus promoting subsequent vascular diseases. This is the result of a study by scientists of Helmholtz Zentrum München, Technische Universität München (TUM) and the Collaborative Research Center SFB 1118 at Heidelberg...
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Out-of-pocket costs exceed what many insured cancer patients expect to pay
Some patients spend a third of household income on cancer care, despite insurance. A third of insured people with cancer end up paying more out-of-pocket than they expected, despite having health coverage, researchers at the Duke Cancer Institute have found. The data showed that costs such as copays and deductibles could lead to financial distress among insured...
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Idhifa approved for some with acute myeloid leukemia
(HealthDay)—Idhifa (enasidenib) has been approved by the U.S. Food and Drug Administration to treat adults with a specific genetic mutation that leads to relapsed or refractory acute myeloid leukemia (AML). The mutation in the IDH2 gene can be diagnosed with a newly approved companion diagnostic, the RealTime IDH2 Assay, the agency said in a news...
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Lupus treatment generates positive results in Phase III clinical trial
New research indicates that belimumab, a monoclonal antibody therapy that targets a component of the immune system, provides considerable benefits to patients with systemic lupus erythematosus (SLE), a predominately female, chronic inflammatory disease that can affect virtually any organ. The Arthritis & Rheumatology findings are encouraging because lupus is among the leading causes of death in young women. SLE...
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Key factor in development of Parkinson’s disease identified
Purdue University researchers Jean-Christophe “Chris” Rochet and Dr. Riyi Shi say their discovery of a key factor in the development of Parkinson’s disease could lead to new therapies, potentially including drugs currently on the market; A molecule has been identified that appears to play an important role in the development of Parkinson’s disease, a debilitating disease that...
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Synthetic biology approaches to improving immunotherapy
The AACR 2018 Meeting in Chicago is ending today and has featured the major new results in cancer treatment and immunotherapy treatments in particular. Immunotherapy, the use of the patient’s own immune system to attack their cancer, has become a hot area of research and clinical development. While there are several ways in which researchers are approaching immunotherapy, here...
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Mechanism behind neuron death in motor neurone disease and frontotemporal dementia discovered
Scientists have identified the molecular mechanism that leads to the death of neurons in amyotrophic lateral sclerosis (also known as ALS or motor neurone disease) and a common form of frontotemporal dementia. The researchers from the University of Cambridge and University of Toronto also identify potential therapeutic targets for these currently incurable diseases. ALS is a progressive and terminal disease...
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Russian scientists learned to perform the diagnose by analyzing saliva
Researchers developed a unique method of immune diseases diagnosing the symptoms appear. Nature endowed the human with a unique protective system, the immunity. It is capable to protect the body from different external and internal effects. However, disorders of the immune system lead to various diseases from allergy and type I diabetes to more dangerous autoimmune...