Berkeley — Injuries can’t heal without a constant influx of blood’s key ingredient — oxygen. A new flexible sensor developed by engineers at the University of California, Berkeley, can map blood-oxygen levels over large areas of skin, tissue and organs, potentially giving doctors a new way to monitor healing wounds in real time. IMAGE: A NEW...
Among heart attack survivors, drug reduces chances of second heart attack or stroke
AURORA, Colo. (Nov. 7, 2018) – In a clinical trial involving 18,924 patients from 57 countries who had suffered a recent heart attack or threatened heart attack, researchers at the University of Colorado Anschutz Medical Campus and fellow scientists around the world have found that the cholesterol-lowering drug alirocumab reduced the chance of having additional...
Will tarloxotinib finally break the HER2 barrier in lung cancer?
The HER2 gene is a well-known driver of breast cancer, where changes in this gene are found in about 1-in-5 cases of the disease. HER2 also contributes to about 3 percent of lung cancers, representing about 6,500 patients per year. But while drugs like trastuzumab and lapatinib have proven effective in silencing the action of...
One type of brain cell might hold key to inflammation after head injury
SAN DIEGO – By eliminating one type of immune cell in the brain, researchers were able to erase any evidence of inflammation following traumatic brain injury, according to a new study from The Ohio State University. “We used a drug to wipe out cells called microglia in mice that had experienced brain injury, and the...
Can stimulating the brain treat chronic pain?
An EEG of a naturally occurring alpha oscillation in a human brain. Enhancing these electric oscillations may help treat people with depression. Credit: University of North Carolina Health Care For the first time, researchers at the UNC School of Medicine showed they could target one brain region with a weak alternating current of electricity, enhance...
Marijuana use tied to serious diabetes complication
Called diabetic ketoacidosis (DKA), the condition occurs when there is not enough insulin to break down sugar in the body, so the body burns fat for fuel instead. This triggers a build-up of chemicals known as ketones, which make blood more acidic and can lead to coma or death. “About 30 percent of our patients...
Combination chemotherapy and immunotherapy effective in Phase II leukemia study
A combination of the standard-of-care chemotherapy drug known as azacitidine, with nivolumab, an immune checkpoint inhibitor, demonstrated an encouraging response rate and overall survival in patients with relapsed or refractory acute myeloid leukemia (AML) according to findings from a Phase II study at The University of Texas MD Anderson Cancer Center. Results from the trial,...
Calcifications in the eye increase risk for progression to advanced AMD by more than six times
Calcified nodules in the retina are associated with progression to late stages of age-related macular degeneration (AMD). Experts from Queen’s University Belfast, working in partnership with the University of Alabama of Birmingham and in collaboration with UK material scientists and US clinical ophthalmology practices, made the ground-breaking discovery that the calcified nodules in the retina...
Blue light can reduce blood pressure
Exposure to blue light decreases blood pressure, reducing the risk of developing cardiovascular disease, a new study from the University of Surrey and Heinrich Heine University Dusseldorf in collaboration with Philips reports. Credit: CC0 Public Domain During this study, published in the prestigious European Journal of Preventative Cardiology, participants were exposed to 30 minutes of...
Novel discovery could lead to new cancer, autoimmune disease therapy
Scanning electron micrograph of human T lymphocyte or T cell. Credit: NIAID/NIH A new discovery by an international research team—co-led by UBC Canada 150 Research Chair Josef Penninger and Harvard Medical School neurobiologist Clifford Woolf—could have implications for therapies for cancer and autoimmune diseases. Credit: NIAID/NIH In a study published today in Nature, researchers outline...