Month: <span>April 2019</span>

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The unusual rash that turned out to be a sign of anal cancer

The woman had the strange rash for 11 months before seeing a doctor   But then she started experiencing vomiting, diarrhoea and stomach pains Tests revealed cancer – and the rash disappeared during treatment Dermatologists have said the rash is a sign of cancer but is very rare By VANESSA CHALMERS HEALTH REPORTER FOR MAILONLINE PUBLISHED: 09:18 EDT, 12 April 2019 | UPDATED: 09:59 EDT, 12 April 2019 A woman who was concerned...

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Parents of severely autistic schoolboy, 11, who could not talk claim he has said his first full sentence after ‘very encouraging’ stem-cell treatment in Miami

Danny Bullen had the treatment last month and should have a second this year  The next day his mother claims he asked for ‘more potatoes [crisps] please’ The youngster needs help going to the toilet and attends a specialist school The parents of an autistic schoolboy claim he spoke his first full sentence just hours after undergoing stem-cell therapy in the...

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Scientists on the cusp of curing blindness with pioneering treatment that injects stem cells into the back of patients’ eyeballs

British firm reported early success with procedure that repairs damaged retina Treatment involves growing billions of ‘progenitor’ stem cells in a laboratory Have the ability to transform themselves into other types of cell There is no cure for retinitis pigmentosa, which slowly constricts vision By STEPHEN ADAMS FOR THE MAIL ON SUNDAY PUBLISHED: 20:44 EDT, 13 April 2019 | UPDATED: 02:58 EDT, 14 April 2019 Victims...

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Drug reduces risk of kidney failure in people with diabetes, study finds

by Amy Jeter Hansen,  Stanford University Medical Center A new landmark clinical trial shows that a drug lowers the risk of kidney failure by a third in people with Type 2 diabetes and kidney disease. “For the first time in 18 years, we have a therapy for patients with Type 2 diabetes and chronic kidney disease that decreases kidney failure,” said Kenneth Mahaffey, MD, professor...

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Simple test can indicate prolonged symptoms following pediatric sports-related concussion

JOURNAL OF NEUROSURGERY PUBLISHING GROUP CHARLOTTESVILLE, VA (APRIL 16, 2019). Researchers from Children’s Hospital Colorado and the University of Colorado School of Medicine in Aurora, Colorado, have found that abnormal performance on the Romberg balance test can indicate that children and adolescents will experience prolonged symptoms following sports-related concussion. This finding is reported today in a new article by David R. Howell, PhD, and...

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Mindful body awareness training during treatment for drug addiction helps prevent relapse

Date: April 16, 2019 Source: University of Washington Summary: A novel type of body awareness training helps women recover from drug addiction, according to new research. People in the study made marked improvement, and many improvements lasted for a year. A novel type of body awareness training helps women recover from drug addiction, according to...

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Novel, ‘Non-Habit Forming’ Medication May Reduce Low Back Pain

Nancy A. Melville April 10, 2019 This story was revised April 12 with additional comments. MILWAUKEE — A novel, “non-habit-forming” neurosteroid appears to be effective and well tolerated in the treatment of chronic low back pain, new research suggests. In a double-blind, randomized controlled trial of almost 100 Iraq/Afghanistan-era veterans, those treated with a pharmaceutical-grade tablet...

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What Are Polygenic Scores and Why Are They Important?

Leo P. Sugrue, MD, PhD1; Rahul S. Desikan, MD, PhD1,2 Author AffiliationsArticle Information JAMA. Published online April 8, 2019. doi:10.1001/jama.2019.3893 Mendelian disorders and monogenic traits result from combinations of variants in 1 or a few genes that have a large effect on the propensity for developing a certain disease or characteristic. In contrast, complex traits, such as eye color or cardiovascular disease, are determined by...

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Studies identify mechanism key to removal of protein aggregates from cells

Mass. General team’s findings may have application to treatment of cancer, neurodegenerative disorders MASSACHUSETTS GENERAL HOSPITAL Massachusetts General Hospital (MGH) investigators have discovered the mechanism by which cells sense dysfunction of the proteasome – a cellular component that degrades unneeded or defective proteins – and respond in a previously undescribed manner, by editing the amino acid sequence of a key sensing protein....

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Nanobodies’ from alpacas could help bring CAR T-cell therapy to solid tumors

Unusually small antibodies, targeted to the tumor micro-environment, curb melanoma and colon cancer in mouse models BOSTON CHILDREN’S HOSPITAL In 1989, two undergraduate students at the Free University of Brussels were asked to test frozen blood serum from camels, and stumbled on a previously unknown kind of antibody. It was a miniaturized version of a...