The drug was approved for patients with TGCT with severe morbidity or functional limitations that has not improved with surgery. Turalio is only available through the Risk Evaluation and Mitigation Strategy Program. Approval was based on data from a multicenter international clinical trial of 120 patients. After 25 weeks, patients who received Turalio had a...
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Fecal transplants result in massive long-term reduction in autism symptoms
Scientific research continues to uncover interesting connections between the gut microbiome and human health, including everything from depression to PTSD to autoimmune disease. Another example of this are the emerging ties between gut health and autism, with an exciting new study demonstrating how boosting microbial diversity via fecal transplants can dramatically reduce its symptoms in...
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Reality check on Lilly’s new, cheaper insulin
Eli Lilly’s decision to start selling a new version of its most popular fast-acting insulin highlights the industry’s concerns about possible legislation or regulation to rein in drug prices. Reality check: Some diabetic patients will benefit from Lilly’s new authorized generic, called Lispro. But the PR-heavy move, which has been replicated for other controversially priced medicines, isn’t structural change. It aligns with the Trump administration’s goal...
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Study explores dose ranges for efpeglenatide in early T2DM
Julio Rosenstock, M.D., from the Dallas Diabetes Research Center at Medical City, and colleagues evaluated the safety and efficacy of once-weekly efpeglenatide, a long-acting glucagon-like peptide 1 receptor agonist (GLP-1 RA), in early type 2 diabetes (drug naive or on metformin monotherapy [90 percent]). Among the participants, 181 were randomly assigned to one of five...
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Liver Damage More Common Due to Malignant Tumors than Cancer Immunotherapy Drug
Posted Yesterday Immunotherapy as a treatment for advanced solid organ tumors has rapidly evolved over the past decade, often yielding remarkable results. However, its use has also given way to new adverse effects, including drug-induced gastrointestinal and liver toxicities. “Checkpoint inhibitors are a game changer for a lot of oncology patients with previously untreatable tumors,” says Robert Fontana, M.D., University of Michigan’s medical...
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‘TEACH BACK’ COMMUNICATION CAN KEEP YOU OUT OF THE HOSPITAL
In the study, people living with high blood pressure, Type 2 diabetes, and heart disease—conditions that can result in hospital visits if not managed effectively at home or with a patient’s primary care doctor—saw double-digit drops in hospital admissions compared with patients who did not teach their instructions back to their health-care provider. “For patients...
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#HelloMyNameIs: A simple act to improve patients’ experiences of care
by Maisam Najafizada, Arifur Rahman And Katie Oxford, The Conversation In 2011, Dr. Kate Granger, a British geriatrician was diagnosed with cancer and her subsequent hospital stays and visits began. As a care provider, she noticed something simple, yet significant, that was often missed by the hospital staff. When staff showed up with updates on...
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HRT MAY BOOST HEART FAT IN MENOPAUSAL WOMEN
The findings highlight a new risk factor for cardiovascular disease in midlife women and reinforce the importance of tailoring hormone therapy to each patient. Importantly, researchers found that the formulation and delivery route of hormones—whether as a pill taken orally or a patch placed on the skin—mattered when it came to the types of fat...
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Atrial fibrillation common and incurable, but controllable
by Scott Gilbert, Pennsylvania State University One of the most common problems cardiologists handle is atrial fibrillation, also called AFib or AF. AFib is an abnormal or irregular heartbeat that can lead to blood clots, stroke, heart failure and other heart-related complications. As many as 6 million people in the United States and 33 million people...
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CAVA Device Spots Nystagmus to Diagnose Dizziness
Dizziness is a common condition but its underlying causes can be very difficult to diagnose. It is usually unpredictable and doesn’t last very long, so by the time a patient presents to the physician everything checks out as normal. Detecting nystagmus (uncontrolled eye movements) is a pretty reliable way of diagnosing peripheral vestibular disorders, but the randomness and rarity...