by Goethe University Frankfurt am Main In glioblastoma cells, the antidiarrheal drug loperamide triggers the degradation of the endoplasmic reticulum. In the normal state, it is coloured yellow in these microscopic images. In the degradation state, it glows as a red signal (marked with arrows). Left scale bar: 20 µm, right scale bar (inset): 5 µm....
by University of Chicago Medical Center Study participants using the neuroprosthetic device shown in the diagram on the left all reported little change in the location of the sensation provided by their device, feeling it in their middle finger, palm, or at the base of the thumb rather than at the tip of their thumb, despite...
By Angela Betsaida B. Laguipo, BSN Dec 3 2020 The coronavirus disease (COVID-19) pandemic has rapidly spread worldwide, infecting over 64.50 million people across 191 territories. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the infection has already claimed more than 1.49 million lives. The coronavirus pandemic is by far the worst global...
For the first time, scientists at the University of Zurich have been able to observe stem cells in the adult mouse brain that divide over the course of several months to create new nerve cells. The study shows that brain stem cells are active over a long period, and thus provides new insights for stem...
For the first time, a new study shows that treatment with a progesterone receptor modulator is effective for the treatment of typical symptoms such as irritability and depression in women suffering from PMDS. The study, which was conducted at Uppsala University, Karolinska Institute and Umeå University, has been published in the medical journal American Journal...
LIVERPOOL SCHOOL OF TROPICAL MEDICINE A previous version of the Cochrane review, consisting of 63 trials, seemed to show probiotics were effective. In this update, the addition of new trials, including two large well-conducted trials; the finding of substantive publication bias; and the use of GRADE led to a change in the authors’ assessment of...
by Virginia Tech Michael Fox, a professor at the Fralin Biomedical Research Institute at VTC and director of the School of Neuroscience in Virginia Tech’s College of Science, led a study that may help reveal the molecular underpinnings of seizures and psychiatric disorders. Credit: Virginia Tech A research team led by Michael Fox, a professor at...
by Stacy Kish, University of California – Riverside Image shows astrocytes (green) in MS hippocampus. Credit: Tiwari-Woodruff lab, UC Riverside. A research team at the University of California, Riverside School of Medicine has identified a pathway involving astrocytes, a class of central nervous system support cells, that could shed light on why seizures happen in a subset of...
UNIVERSITY OF ALABAMA AT BIRMINGHAM BIRMINGHAM, Ala. – A potential preventive treatment for Crohn’s disease, a form of inflammatory bowel disease, has been demonstrated in a mouse model and using immune-reactive T cells from patients with Crohn’s disease. This research, led by University of Alabama at Birmingham researcher Charles O. Elson, M.D., professor of medicine, focused...
HERSHEY, Pa. — The absence of a protein that works to prevent tumor formation may explain why some patients are resistant to a common cancer therapy, according to Penn State College of Medicine researchers. They said that testing cancers for the presence of this protein may help clinicians identify patients who may be resistant to or...
