ELIFE IMAGE: A MICROSCOPY IMAGE OF LEPTOSPIRA BACTERIA CREDIT: WUNDER ET AL. (CC BY 4.0) Scientists have designed a single-dose universal vaccine that could protect against the many forms of leptospirosis bacteria, according to a study published today in eLife. An effective vaccine would help prevent the life-threatening conditions caused by leptospirosis, such as Weil’s disease...
by Lisbeth Heilesen, Aarhus University Researchers from Aarhus University have discovered that ITIH4 inhibits proteases in the innate immune system via an unknown mechanism. Credit: Rasmus Kjeldsen Jensen. Although the protein ITIH4 is found in large amounts in the blood, its function has so far been unknown. By combining many different techniques, researchers from Aarhus University have discovered that...
by Marilynn Marchione This photo provided by Eli Lilly shows the drug bamlanivimab. On Tuesday, Jan. 26, 2021, the company said that the two-antibody combo of bamlanivimab and etesevimab reduced the risk of hospitalizations or death by 70% in newly diagnosed, non-hospitalized COVID-19 patients at high risk of serious illness because of age or other...
Heart disease deaths have declined among older people, but the trend is less encouraging among younger people, particularly women. Indeed, research suggests that heart disease and death rates from heart disease in these younger groups have remained unchanged or have even gone up slightly. To understand which factors put younger individuals at higher risk of premature coronary...
MICROBICIDE TRIALS NETWORK PITTSBURGH, 26 January 2021 – A vaginal ring containing the antiretroviral drug dapivirine and the contraceptive hormone levonorgestrel delivered sustained levels of each drug when used continuously for 90 days – levels likely sufficient to serve its dual purpose for protecting against both HIV and unwanted pregnancy, according to findings of a...
by University of California – San Diego Micrograph showing a lymph node invaded by ductal breast carcinoma, with extension of the tumour beyond the lymph node. Credit: Nephron/Wikipedia Restricting eating to an eight-hour window, when activity is highest, decreased the risk of development, growth and metastasis of breast cancer in mouse models, report researchers at University of California...
by Ludwig Maximilian University of Munich A nerve cell with its dendritic processes studded by synaptic spines (red) being contacted by brain-resident microglia cell (blue) in a mouse brain. Credit: Misgeld & Kerschensteiner Multiple sclerosis (MS) is a chronic inflammatory disease that affects the central nervous system, in which nerve cells are attacked by the patient’s...
by Karolinska Institutet Anna Smed Sörensen, associate professor at the Department of Medicine, Solna, Karolinska Institutet. Credit: Ulf Sirborn Individual variations in how the immune system responds to SARS-CoV-2 appear to impact the severity of disease. Researchers at Karolinska Institutet in Sweden have now been able to show that patients with severe COVID-19 have significantly elevated levels of...
by Bill Hathaway, Yale University Credit: Unsplash/CC0 Public Domain A little more than a year ago, as the first reports rolled in about the outbreak of a novel new coronavirus in China, it quickly became clear that older individuals and males were most at risk of lethal outcomes. Yale immunobiologist Akiko Iwasaki knew immediately that studying...
By MATTHEW HERPER @matthewherper JANUARY 23, 2021 NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, NIH Apress release from a Canadian research group raised hopes that treating people recently diagnosed with Covid-19 with colchicine, a drug commonly used to treat gout, could reduce the risk they will need to be hospitalized. But outside experts said the data provided were too...
