by University of Turku Fig. 1: Study sample and gut microbiome characteristics. a At baseline, the study sample (n = 7211) had a balanced sex ratio (55% women in red:men in blue), a mean age of 49 years (range 24–74; left panel) and a mean body mass index (BMI) of 27 kg/m2 (range 16–57; middle panel). During...
By Megan Molteni A natural killer cellNIAID Scientists have started to test whether natural killer, or NK, cells can be trained to go after hard-to-cure blood cancers in human patients. But making these sentinels of the innate immune system a potential boon to human health spans might be simpler: Rather than needing to be genetically engineered...
by CU Anschutz Medical Campus Credit: CC0 Public Domain Looking to safely block a gene linked to factors known to cause heart disease, scientists at the University of Colorado Anschutz Medical Campus may have found a new tool—light. The study, published Monday in the journal Trends in Molecular Medicine, may solve a medical dilemma that has baffled...
Max GelmanAssociate EditorAfter earning priority review for a top CKD and diabetes program back in January, Bayer is revealing more data that it hopes will boost its pitch to regulators. Bayer’s finerenone has passed another Phase III test, the pharma announced Monday, saying the candidate met the primary endpoint in a second study evaluating treatment...
by Tufts University Credit: CC0 Public Domain Speech problems such as stammering or stuttering plague millions of people worldwide, including 3 million Americans. President Biden himself struggled with stuttering as a child and has largely overcome it with speech therapy. The cause of stuttering has long been a mystery, but researchers at Tufts University are beginning to unlock...
By Sally Robertson, B.Sc. May 10 2021 Researchers in the United States have shown that genes from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the causative agent of coronavirus disease 2019 (COVID-19) – can be integrated into the genome of infected human cells. The team says the viral RNA can be expressed as chimeric transcripts...
Researchers have been able to reduce scarring by blocking part of the healing process in research that could make a significant difference for burns and other trauma patients. University of Queensland Professor Kiarash Khosrotehrani said scars had been reduced by targeting the gene that instructs stem cells to form them in an animal study. Image credit: chezbeate via Pixabay,...
Researchers at the University of Alberta have developed a method to 3D print cartilage-like materials consisting of a collagen hydrogel containing human chondrocytes. The printed structures mimic human nasal cartilage in terms of its mechanical, molecular and histological characteristics. The researchers hope the technology could lead to personalized cartilage implants for skin cancer patients who have nasal cartilage...
UNIVERSITY OF CALIFORNIA – SAN FRANCISCO Scientists at UC San Francisco are learning how immune cells naturally clear the body of defunct – or senescent – cells that contribute to aging and many chronic diseases. Understanding this process may open new ways of treating age-related chronic diseases with immunotherapy. In a healthy state, these immune...
UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE PHILADELPHIA– New research performed in mice models at Penn Medicine shows, mechanistically, how the infant lung regenerates cells after injury differently than the adult lung, with alveolar type 1 (AT1) cells reprograming into alveolar type 2 (AT2) cells (two very different lung alveolar epithelial cells), promoting cell regeneration, rather than AT2...
