There are many types of memory, but fundamentally, humans remember in two ways. Declarative memory consists of ordinary recollections consciously summoned from the brain. It is dependent on the medial temporal lobe (MTL), which in turn contains key cognitive structures, including the hippocampus and entorhinal cortex. Declarative memory allows us to explicitly recall or recognize...
New study determines cystic fibrosis therapy is safe and effective for young children
CHILDREN’S HOSPITAL COLORADO IMAGE: LEAD STUDY AUTHOR JORDANA HOPPE, MD, A PEDIATRIC PULMONOLOGIST WITH CHILDREN’S HOSPITAL COLORADO AND ASSISTANT PROFESSOR OF PEDIATRICS AT THE UNIVERSITY OF COLORADO SCHOOL OF MEDICINE ON THE ANSCHUTZ MEDICAL CAMPUS. CREDIT: CHILDREN’S HOSPITAL COLORADO Children ages two to five who have the most common form of cystic fibrosis (CF), caused...
Exercise can help support recovery of patients with lasting COVID symptoms, study finds
NATIONAL INSTITUTE FOR HEALTH RESEARCH Patients with lasting symptoms of COVID-19 who completed a six week, supervised rehabilitation programme demonstrated significant improvements in exercise capacity, respiratory symptoms, fatigue and cognition, according to researchers at the National Institute for Health Research (NIHR) Leicester Biomedical Research Centre – a partnership between Leicester’s Hospitals, the University of Leicester...
New saliva oral and throat cancer diagnosis test receives FDA approval
by Rose Trapnell, Queensland University of Technology Credit: Queensland University of Technology A QUT researcher’s identification of saliva as an early detection liquid biopsy for oral and throat cancer has been realized by the development and commercialisation of a diagnostic device by US-based biotech company Viome. Viome’s early detection device has been designated a Breakthrough Device...
Nerve stimulation helps restore arm function after stroke
Researchers devise a new approach to regaining movement after stroke. PM Images/Getty Images Strokes often leave people with reduced arm function, which is difficult to regain. While physical therapy may help, full recovery is elusive and becomes even less achievable the more time passes after a stroke. A new study documents what could be a...
One-third of patients hospitalized with severe COVID-19 still have lung changes after a year
by University of Southampton Novel Coronavirus SARS-CoV-2 Transmission electron micrograph of SARS-CoV-2 virus particles, isolated from a patient. Image captured and color-enhanced at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. Credit: National Institute of Allergy and Infectious Diseases, NIH A new study has shown that most patients discharged from hospital after experiencing severe...
Trial demonstrates early AI-guided detection of heart disease in routine practice
by Mayo Clinic Credit: Unsplash/CC0 Public Domain Heart disease can take a number of forms, but some types of heart disease, such as asymptomatic low ejection fraction, can be hard to recognize, especially in the early stages when treatment would be most effective. The ECG AI-Guided Screening for Low Ejection Fraction, or EAGLE, trial set out to...
What is Preclinical Immunogenicity Assessment?
By Michael Greenwood, M.Sc.Reviewed by Sophia Coveney, B.Sc. Assessing the immunogenicity, the ability of a foreign substance to elicit an immune response, of any drug or therapeutic is essential to assessing efficacy and toxicity at the early stages of drug discovery. Image Credit: Sakurra/Shutterstock.com However, traditional small molecule drugs tend not to elicit a significant response compared with biologics...
Reduced kidney function linked to increased risk of dementia
AMERICAN ACADEMY OF NEUROLOGY MINNEAPOLIS – Chronic kidney disease is when a person’s kidneys progressively lose their ability to filter waste from the blood and eliminate fluids. Now a new study has found that people with reduced kidney function may have an increased risk of developing dementia. The study is published in the May 5,...
Which medications are most toxic to the liver?
WILEY A new study published in the British Journal of Clinical Pharmacology ¬provides insights on how common hospitalized patients develop liver injury from taking different medications. When investigators analyzed the records of 156,570 hospitalized patients, they found 499 cases of drug-induced liver injury (DILI), for an incidence of 0.32%. Anti-infective agents, cancer medications, and nonsteroidal...