EXPERIMENTAL BIOLOGY IMAGE: THE RESEARCHERS USED THE PLANT COMPOUND SANGUINARINE TO TREAT TWO GROUPS OF TRIPLE NEGATIVE BREAST CANCER CELLS — ONE DERIVED FROM WOMEN WITH AFRICAN AMERICAN ANCESTRY AND THE OTHER FROM WOMEN OF EUROPEAN ORIGIN. CREDIT: SAMIA MESSEHA, FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY Findings from a new cell study suggest that the natural...
Researchers uncover potential new way to treat dry mouth
EXPERIMENTAL BIOLOGY IMAGE: IN A NEW STUDY, RESEARCHERS FOUND THAT A PDE4 INHIBITOR INCREASED SALIVATION BECAUSE OF PDE4 INHIBITION IN THE SALIVARY GLANDS AND IN THE AUTONOMIC NERVOUS SYSTEM, WHICH REGULATES INVOLUNTARY BODY PROCESSES SUCH AS BREATHING. THE FINDINGS COULD LEAD TO A NEW TREATMENT FOR DRY MOUTH. CREDIT: ABIGAIL BOYD, UNIVERSITY OF SOUTH ALABAMA...
Toward a feasible alternative to liver organ transplant
EXPERIMENTAL BIOLOGY IMAGE: THIS FIGURE SHOWS THE RAT HEPATOCYTE TRANSPLANT AND MICRODISSECTION TECHNIQUE USED IN THE STUDY (TOP) WITH THE TRANSCRIPTOMIC AND HISTONE PROTEOMIC PRINCIPAL COMPONENT ANALYSES SHOWN BELOW. CREDIT: ANDERS OHMAN New insights into how fetal and adult liver cells differ could be used to help make liver cell transplants successful long term. Transplanting...
Salk scientists reveal how brain cells in Alzheimer’s go awry, lose their identity
SALK INSTITUTE IMAGE: THIS IMAGE IS A COMPOSITE OF INDUCED NEURONS (BRAIN CELLS) FROM DIFFERENT INDIVIDUALS WITH ALZHEIMER’S DISEASE. CREDIT: SALK INSTITUTE LA JOLLA–(April 27, 2021) Despite the prevalence of Alzheimer’s, there are still no treatments, in part because it has been challenging to study how the disease develops. Now, scientists at the Salk Institute...
Cholestenone shows antibiotic properties against H. pylori
SHINSHU UNIVERSITY IMAGE: EFFECT OF STEROLS ON HELICOBACTER PYLORI GROWTH AND MORPHOLOGY CREDIT: COPYRIGHT © 2021, JUN NAKAYAMA, SHINSHU UNIVERSITY Helicobacter pylori (H. pylori), a gram-negative pathogen that has infected half of the world’s population is a Group I carcinogen according to the WHO. H. pylori resides in the gastric mucosa causing gastritis, ulcers, gastric...
Breakthrough in the understanding of a protein with a key role in several cancers
UMEA UNIVERSITY The neutron reflexometry method has given scientists an atomic-level insight into the behaviour of Bcl-2, a protein that promotes cancerous cell growth. The new study was carried out by Umeå chemists in collaboration with the research facilities ESS and ISIS and is published in Nature Communications Biology. Elevated function of the cell-protecting membrane protein Bcl-2 can...
Scientists created technology to detect and treat complex arrhythmias
URAL FEDERAL UNIVERSITY IMAGE: THE GRAY DOTS REPRESENT THE MAPPING POINTS WHILE THE BLACK CIRCLE DENOTES THE MITRAL VALVE. CREDIT: FRONT. PHYSIOL. 10:1138. Researchers from Belgium, the Netherlands, Russia, and Italy have developed a breakthrough method for quickly, accurately, and reliably diagnosing cardiac arrhythmias. They called it Directed graph mapping (DGM). The technology principles are published...
A new treatment that might keep COVID-19 patients off the ventilator
OHIO STATE UNIVERSITY COLUMBUS, Ohio – A new treatment is among the first known to reduce the severity of acute respiratory distress syndrome caused by the flu in animals, according to a new study. Tests in mice infected with high doses of influenza showed that the treatment could improve lung function in very sick mice...
Hepatitis C drugs multiply effect of COVID-19 antiviral Remdesivir
RENSSELAER POLYTECHNIC INSTITUTE IMAGE: EXISTING DRUGS FOR HEPATITIS C MULTIPLY THE EFFECT OF THE COVID-19 ANTIVIRAL REMDESIVIR CREDIT: JENNA LEUCKE/U. OF TEXAS AT AUSTIN TROY, N.Y. — When combined with drugs currently used to treat hepatitis C, the antiviral remdesivir is 10 times more effective in treating cells infected with SARS-CoV-2, the virus that causes...
Study reports links between blood types and disease risks
ELIFE People with certain blood types are more likely to have blood clots or bleeding conditions, kidney stones, or pregnancy-induced hypertension, suggests a study published today in eLife. The study confirms previously identified connections between certain blood types and the risk of blood clots and bleeding, and makes a new connection between kidney stones and having...