by Griffith University Fig. 1: Screening of potent repressors of HIV-1 derived from fusion of ZFP362 and combination of repressor domains. a Schematic representation of the design of the ZD3A constructs leading to ZD3A protein. The NLS containing the ZFP362 domain can bind HIV-1 LTR promoter specifically and DNMT3A can recruit epigenetic silencing complexes. The binding...
by Ingrid Fadelli , Medical Xpress Astrocyte responses to inflammation produce many different clusters of ‘reactive’ sub-states. Hasel et al. find that astrocytes respond to acute inflammation by producing many reactive ‘sub-states’ which have defined transcriptomic profiles and spatial locations. This image shows a spatial transcriptomic image projected from the mouse brain onto the screens....
Bone mass and bone mineral density both decrease as people age. Osteopenia is a condition where people’s bone density is lower than is usual for their age. Osteoporosis is a more severe case of bone loss that weakens the bones and makes them more likely to fracture. Bone mass and bone mineral density measure the amount of...
by Mayo Clinic Credit: Pixabay/CC0 Public Domain Heart rhythm disorders are one of the most common cardiac problems. Arrhythmias cause the heart to beat too fast, too slow, or irregularly. People can be born with them or develop them during their lives. Elijah Behr, M.D., a cardiologist at Mayo Clinic Healthcare in London, shares five developments...
UNIVERSITY OF SOUTH AUSTRALIA IMAGE: A RELAXED PARENTING STYLE, EATING TOGETHER AS A FAMILY, AND INVOLVING A CHILD IN FOOD PREPARATION CAN REDUCE THE LIKELIHOOD OF FUSSY EATING. CREDIT: RUDY AND PETER SKITTERIANS FROM PIXABAY Whether it’s an exclusive appetite for ‘white’ foods or an all-out refusal on veggies, when you have a fussy eater...
TOKYO MEDICAL AND DENTAL UNIVERSITY IMAGE: APPEARANCE OF MICE FED WITH A HIGH-FAT DIET (RIGHT) AND A STANDARD DIET (LEFT). CREDIT: DEPARTMENT OF STEM CELL BIOLOGY, TMDU Tokyo, Japan – It’s well known that obesity is linked to the development of numerous diseases in humans. Heart disease, diabetes, and other ailments are extremely common in...
by Karen Schmidt, American Heart Association Credit: CC0 Public Domain A year of exercise training helped to preserve or increase the youthful elasticity of the heart muscle among people showing early signs of heart failure, a small study shows. The new research, published Monday in the American Heart Association journal Circulation, bolsters the idea that “exercise is medicine,”...
Reviewed by Emily Henderson, B.Sc. Sep 20 2021 The test results that hot day in early August shouldn’t have surprised me — all the symptoms were there. A few days earlier, fatigue had enveloped me like a weighted blanket. I chalked it up to my weekend of travel. Next, a headache clamped down on the...
by Morgan Henderson, Morgane Mouslim, The Conversation Credit: Pixabay/CC0 Public Domain Health researchers have long argued that the key to reining in surging health care costs is to tackle the high prices of services, and one potential way to do this is to provide patients with price transparency. That is, if people know how much a...
Pfizer has voluntarily recalled 12 lots of its anti-smoking drug Chantix for containing high levels of cancer-causing agents called nitrosamines According to a notice posted on the FDA’s website ‘the presence of a nitrosamine, N-nitroso-varenicline (NDMA)’ was above acceptable intake ‘The health benefits of stopping smoking outweigh the cancer risk from the nitrosamine impurity in...
