by Ruhr-Universitaet-Bochum Fig. 1. Systematic screening for epigenetic marks showing differential levels between mouse and human bIPs. (A) A scheme of the experimental design used to compare the transcriptomes and epigenomes of mouse and human BPs. (B and C) Purification of Tbr2+ bIPs in developing mouse and human cortex. Representative images of cell suspensions from mouse...
by Aaron Conley, Vanderbilt University Figure 1. Dopamine in the nucleus accumbens core does not track reward prediction error in negative reinforcement tasks (A) Positive reinforcement task. (B) Dopamine was recorded via fiber photometry using dLight1.1. (C) Mice made more active than inactive responses during the post-training session (t6 = 3.18, p = 0.024; n = 6). (D and E)...
by RIKEN Figure 1: A colored transmission electron micrograph of influenza viruses (light brown) budding from a host cell. RIKEN researchers have discovered why live attenuated vaccines are more effective at priming the immune system against influenza viruses than inactivated vaccines. Credit: Steve Gschmeissner/Science Photo Library In a finding that should help researchers develop vaccines that offer broad protection against...
by American Society of Hematology Credit: CC0 Public Domain Heart abnormalities are common complications of sickle cell anemia (SCA) that can contribute to severe disease symptoms and even death. A study published today in the journal Blood Advances is the first to find that hydroxyurea therapy can improve or even reverse cardiac complications in individuals living with SCA. Researchers say...
by American Physiological Society Figure 1. Group means and individual data for flow-mediated dilation (FMD, A), peak blood velocity following cuff release (B) (n = 12 control and n = 16 COVID for both), pulse wave velocity (PWV, C), and augmentation index normalized to heart rate of 75 beats/min (AIx75, D) (n = 10 control and n = 16 COVID for both) between control...
by Kyoto University Credit: Kyoto University Is a new high-income job offer worth accepting if it means commuting an extra hour to work? People often have to make tough choices regarding whether to endure some level of discomfort to take advantage of an opportunity or otherwise walk away from the reward. In making such choices, it...
by Cancer Biology and Medicine Credit: CC0 Public Domain Gliomas are the most common primary brain tumors in adults. Among them, the high-grade glioblastomas (GBMs) are particularly known to be notoriously aggressive and invasive, which makes it challenging to treat them. The disease rapidly progresses to an advanced stage in a short span of time,...
by Kyoto University Credit: Kyoto University The visual cortex makes up one of the largest regions of the brain, which is a testament to how much information we receive from our eyes. The primary visual cortex, or V1, is the first stage of processing visual input in the brain. Without a functional V1, a person is...
by Laurie Fickman, University of Houston Credit: Unsplash/CC0 Public Domain Breathe in, breathe out. That’s how easy it is for SARS-CoV-2, the virus that causes COVID-19, to enter your nose. And though remarkable progress has been made in developing intramuscular vaccines against SARS-CoV- 2, such as the readily available Pfizer, Moderna, and Johnson & Johnson vaccines,...
by Sarah Pitt, The Conversation Credit: ShotPrime Studio/Shutterstock After consulting its vaccine advisers, the UK government is launching its much-discussed COVID-19 vaccine booster program. From the week beginning September 20 2021, a third dose will be offered to all people who were prioritized in the first wave of the UK’s vaccine rollout. This includes all residents and staff of care...
