by National Multiple Sclerosis Society Demyelination by MS. The CD68 colored tissue shows several macrophages in the area of the lesion. Original scale 1:100. Credit: Marvin 101/Wikipedia Researchers at the National Institutes of Health, Johns Hopkins University, and others have published results of studies that map out the activity of genes, molecules, cells, and their interactions...
by American Heart Association News Measuring waist circumference may be an essential way to help predict who will develop diabetes among Black people with normal blood sugar levels, according to a new study. The problem is, researchers say, waist size often is overlooked at health visits. The study, published Wednesday in the Journal of the American Heart Association,...
by Massachusetts Institute of Technology Inhibitory interneurons in the visual cortex (PV cells are green; SST cells are red), combine to regulate the reliability of image representation by excitatory neurons. Credit: Murat Yildirim/MIT Picower Institute When it comes to processing vision, the brain is full of noise. Information moves from the eyes through many connections in...
By Michael Irving September 07, 2021 Tiny lab-grown mini-brains have now been induced to show pathology features of Parkinson’s disease Associate Professor Hyunsoo Shawn Je, Duke-NUS Medical School. To help us crack the complex puzzle that is our own brains, scientists have been growing miniature versions in the lab. Now, a team in Singapore has...
By Sally Robertson, B.Sc. Sep 8 2021 Researchers in Texas have provided evidence for the need to modify the currently used coronavirus disease 2019 (COVID-19) vaccines to match circulating variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The team from the University of Texas Medical Branch in Galveston showed the distinct cross-neutralizing profiles that were...
Berkeley Lab researchers helped validate new AI-based algorithm, RosETTAFold, to generate hundreds of new protein structures. 3D view of human interleukin-12 bound to its receptor. Photo credit: Ian Haydon / Berkeley Lab “The dream of predicting a protein shape just from its gene sequence is now a reality,” said Paul Adams, Associate Laboratory Director for Biosciences at...
Natural killer cells do not just kill cancer cells or cells infected with viruses, they also mediate a trade-off between wound healing and bacterial defense in skin wounds. If the healing process is accelerated, the immune defense is weakened, researchers at the University of Zurich have now shown. This has relevance in treating skin injuries and in...
BUCK INSTITUTE FOR RESEARCH ON AGING IMAGE: THESE C. ELEGANS HAVE BEEN EXPOSED TO MITOCHONDRIAL STRESS THAT INDUCE PROTEIN MISFOLDING IN THEIR MITOCHONDRIA, WHICH ACTIVATES A GFP REPORTER THROUGHOUT THE BODY OF THE WORM. CREDIT: SUZANNE ANGELI, PHD, BUCK INSTITUTE FOR RESEARCH ON AGING Every cell in the body goes through thousands of chemical reactions...
MASSACHUSETTS EYE AND EAR INFIRMARY Key Takeaways: Gene-based AAVCOVID vaccine employs a unique adeno-associated viral vector (AAV) technology that was shown in non-clinical, nonhuman primate studies to enable protection from SARS-CoV-2 challenge and to induce sustained antibody and cellular immune responses from a single dose for up to a year Production of the vaccine was...
OSAKA UNIVERSITY Mitsubishi Tanabe Pharma Corporation (MTPC, Head Office: Chuo-ku, Osaka; President & Representative Director, CEO: Hiroaki Ueno) and Professor Toshihide Yamashita at the Department of Molecular Neuroscience and Department of Neuro-Medical Science, Osaka University Graduate School of Medicine, announced today that MTPC’s research and development subsidiary in the US, Mitsubishi Tanabe Pharma Development America, Inc. (MTDA)...
