by Autonomous University of Barcelona Image of a human cerebral artery (above) and a mouse cerebral artery (below) obtained using Raman microspectroscopy. The sphingosine-1-phosphate, located mainly in the arachnoid membrane, can be seen in pink. Credit: Autonomous University of Barcelona The arachnoid is one of the three meninges, or brain membranes, and is responsible for mechanically...
Multiple sclerosis linked to infection in adolescence
by Scott Montgomery, The Conversation Credit: New Africa/Shutterstock Multiple sclerosis (MS) is most often diagnosed between the ages of 20 and 50. Certain genes put a person at greater risk of getting this disease of the central nervous system, but scientists are still trying to understand the triggers. My colleagues and I have been studying these...
The influence of pheromonal signals on memory generated in the hippocampus
by Asociacion RUVID Fig. 1: Behavioral setup: configuration based on virtual environments. a Subjects were head-fixed to metal bars, in turn connected to a stereotaxic frame. Movement was only allowed in a single dimension through a low-friction Styrofoam cylinder placed in front of a curved TFT screen. The movements of the cylinder were recorded by an...
Building a better bioartificial pancreas
by Brigham and Women’s Hospital A convection-enhanced encapsulation device as pictured enhances nutrient transport leading to improved survival and improved glucose responsive insulin secretion of the transplanted beta cells. Credit: Randal McKenzie More than 40 million people worldwide are affected with type 1 diabetes (T1D) mellitus, an autoimmune disease in which insulin producing β-cells in the...
India’s DNA COVID vaccine is a world first – more are coming
Smriti Mallapaty ZyCoV-D is the first DNA vaccine for people to be approved anywhere in the world.Credit: Zydus CadilaIndia has approved a new COVID-19 vaccine that uses circular strands of DNA to prime the immune system against the virus SARS-CoV-2. Researchers have welcomed news of the first DNA vaccine for people to receive approval anywhere in the...
Study finds a restricted number of possible escape mutations for SARS-CoV-2 Delta variant
By Dr. Tomislav Meštrović, MD, Ph.D. Sep 5 2021 The emergence of escape mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is somewhat less likely for the Delta variant in comparison with the original or wild type virus, shows a recent study currently available on the bioRxiv* preprint server while it undergoes peer review. Study: Epistasis...
CONCUSSION RECOVERY TAKES UP TO 28 DAYS, NOT 14
“Normal return-to-play time was previously set at 14 days–meaning 50% of people recovered in that time. Our paper suggests that 28 days more fully encapsulates the recovery process. At that point, 85% of people have returned to play,” says Steve Broglio, director of the University of Michigan Concussion Center. The study, which appears in the...
Measuring brain pressure can become big business
A new invention may be on the verge of replacing a costly cranial surgical procedure currently being performed on some traffic accident victims and other patient groups. The ultrasound-based technology has now been granted CE approval for the European market. “We’re through the eye of the needle on this one”, says Tormod Selbekk. Selbekk is...
New therapeutic target discovered for a number of aggressive cancers
A protein in tumour cells could be targeted to treat some types of aggressive cancer including brain, blood, skin, and kidney, new research has shown. The scientists, from the Wellcome Sanger Institute, University of Cambridge and Harvard University, have identified a protein that plays a key role in transforming normal tissue into cancer, as a possible target...
Schizophrenia study suggests advanced genetic scorecard cannot predict a patient’s fate
THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE With the help of cutting-edge computer programs, researchers at the Icahn School of Medicine at Mount Sinai went through the genetic and medical records of more than 8,000 schizophrenia patients. They found that a tool commonly used in research for evaluating a person’s genetic risk...