by Delthia Ricks , Medical Xpress CT images of the brain from two siblings and a cousin with familial Alzheimer’s disease who harbored the Uppsala APP mutation. Credit: M. Pagnon de la Vega et al., Science Translational Medicine (2021) A newly discovered gene mutation linked to early onset Alzheimer’s disease has been discovered by an international team...
Exclusive: research finds small rise in exposure to air pollution leads to higher risk of needing treatment An orange sky over the City of London. Levels of air pollution in London have fallen in recent years. Photograph: Michael Heath/AlamyDamian Carrington Environment editor@dpcarringtonFri 27 Aug 2021 07.26 EDT Exposure to air pollution is linked to an increased severity of mental...
by McGill University Credit: Unsplash/CC0 Public Domain McGill University researchers identify proteins that drive cancer stem cells. Targeting and supressing a particular protein called galectin1 could provide a more effective treatment for glioblastoma, in combination with radiation therapy. Due to its resistance to therapy, glioblastoma is the most common and aggressive cancerous brain tumor in adults. It grows...
by University College London A montage of three images of single striatal neurons transfected with a disease-associated version of huntingtin, the protein that causes Huntington’s disease. Nuclei of untransfected neurons are seen in the background (blue). The neuron in the center (yellow) contains an abnormal intracellular accumulation of huntingtin called an inclusion body (orange). Credit: Wikipedia/...
by University of California – San Diego This image, taken by confocal microscopy, shows a blood vessel. The protein actin, which helps make up the skeleton of a cell, is labeled in green. Thrombin, a pro-inflammatory mediator, causes gaps between blood vessel barrier cells. When the immune system is over-activated, as occurs in sepsis, blood vessels...
by Baylor College of Medicine Samples of SARS-CoV-2 Mpro molecules tested in this work. Credit: The authors / PNAS, 2021 Much progress has been made on the development of vaccines aiming at triggering human immunity to SARS-CoV-2, the virus that causes COVID-19. In addition, researchers at Baylor College of Medicine are involved in the development of antiviral drugs to treat...
by National University of Ireland, Galway CÚRAM Implantable Stimulator Device showing piezoelectric material and insert image of fiber scaffold taken using a scanning electron microscpe. Credit: Manus Biggs/Marc Fernandez Researchers at CÚRAM, the SFI Research Centre for Medical Devices based at NUI Galway, have shown how the simple act of walking can power an implantable stimulator device to speed...
by Brigham and Women’s Hospital Credit: CC0 Public Domain Vaccines are designed to induce a strong and long-lasting immune response through the creation of memory T cells and B cells. The Measles-Mumps-Rubella (MMR) vaccine, given during early childhood, and Tetanus-Diphtheria-Pertussis (Tdap) vaccine, given every 10 years, are known to elicit a protective response against the diseases...
by Wiley Credit: Wiley-VCH Therapies should be highly effective and as free as possible of side effects—a big challenge, particularly in the case of cancer. A Chinese research team has now developed a novel form of photodynamic tumor therapy for the treatment of deep tumors that works without external irradiation. The light source is built into the drug...
by University of California – San Diego Lung organoids are human stem cell-derived “mini lungs” in a laboratory dish. Credit: UC San Diego Health Sciences Since the COVID-19 pandemic reached the United States in early 2020, scientists have struggled to find laboratory models of SARS-CoV-2 infection, the respiratory virus that causes COVID-19. Animal models fell short;...
