by Ellen Goldbaum, University at Buffalo Credit: Pixabay/CC0 Public Domain A type of acupressure focused on pressure points in the ear could be a promising treatment for functional abdominal pain disorder (FAPD), a challenging group of disorders that cause chronic abdominal pain in 13.5% of children and adolescents. That’s the finding from a pilot study published last month...
Researchers studying diet composition, with no weight loss, to treat Type 2 diabetes
by Adam Pope, University of Alabama at Birmingham The study, led by Barbara Gower, Ph.D., is the first randomized clinical trial of a hypothesis that reducing fat stored around organs, through diet alone, can rescue beta-cell function. Credit: University of Alabama at Birmingham A clinical trial now enrolling at the University of Alabama at Birmingham is...
Bacteria blasting cancer treatment shows promise
by Australian National University Associate Professor Aude Fahrer. Credit: Jamie Kidston/ANU A low-cost, non-toxic cancer treatment has been developed by researchers at The Australian National University (ANU). The treatment uses dead bacteria to help kick-start the immune system and shrink cancer. Lead researcher Associate Professor Aude Fahrer says an ongoing Phase 1 clinical trial at The Canberra Hospital...
Chronic-inflammatory liver disease therapy with synthetic bile acid also directly affects the immune system
by Medical University of Vienna Chronic-inflammatory liver disease: Therapy with synthetic bile acid also directly affects the immune system. Credit: Nerthuz/Shutterstock Primary sclerosing cholangitis (PSC) is a rare, chronic inflammatory disease of the bile ducts and difficult to treat. Studies conducted by the Division of Gastroenterology and Hepatology at MedUni Wien under the guidance of Michael...
Discovery of mechanics of drug targets for COVID-19
A team of international researchers, including McGill Professor Stéphane Laporte, have discovered the working mechanism of potential drug targets for various diseases such as cancer, rheumatoid arthritis, and even COVID-19. The findings published in Molecular Celluncover the inner workings of cell receptors that are involved in cancer progression and inflammatory diseases. “The complement system is an integral part...
Antidepressants inhibit cancer growth in mice
by University of Zurich Fig. S1. Syngeneic murine tumor cell growth & efficacy of serotonin depletion and reconstitution therapies in Wt and Tph1-/- mice. (A and B) Tumor weight at the end of the experiment after s.c. injection of syngeneic murine 5*105 MC38 (day 28) and 1*106 Panc02 cell lines (day 35) in Wt and Tph1-/-...
How SNPs can be used to detect disease pathways
IMAGE: SAURABH SINHA, LEFT, AND XIAOMAN XIE DEVELOPED VARSAN TO DETECT DISEASE PATHWAYS USING SINGLE-NUCLEOTIDE POLYMORPHISMS. CREDIT: N/A Researchers at the University of Illinois Urbana-Champaign have developed a new computational tool that can identify pathways related to diseases, including breast and prostate cancer, using single-nucleotide polymorphisms. SNPs, which refer to mutations in a person’s DNA, are...
Live shingles vaccine shows safe, short-term efficacy for persons taking TNFis for inflammatory diseases
1. Live shingles vaccine shows safe, short-term efficacy for persons taking TNFis for inflammatory diseases A randomized controlled trial found that the live shingles, or varicella-zoster, vaccine was safe and showed short-term efficacy for participants also taking tumor necrosis factor inhibitors (TNFis) for a broad range of inflammatory disorders. These finding suggest that a live virus...
Messenger RNA could fight diseases such as Alzheimer’s and cancer, with help from science
by Audra Book, University of Virginia Credit: Audra Book, UVA Engineering Communications This year, the public was introduced to messenger ribonucleic acid, or mRNA, when it became a hero in the worldwide race to develop COVID-19 vaccines. Scientists lab-engineered mRNA to instruct human cells how to recognize, and then destroy, the spike protein that is the...
Study shows screening device accurately detects amblyopia (lazy eye)
by National Eye Institute Within seconds of the screening, the pediatric vision screener device calculates a binocularity score based on foveal alignment and provides a “pass” or “refer” result to the clinician. Credit: Andrew Schuman, M.D. A handheld screening device that detects subtle misalignment of the eyes accurately identifies children with amblyopia (lazy eye), according to...