Senolytic treatments are those that selectively destroy senescent cells, a form of intervention that has produced rejuvenation in older animals. A high dose of the flavonol fisetin is not yet proven to be usefully senolytic in humans, but has shown a surprising degree of efficacy in mice. The only senolytic therapy demonstrated to clear senescent...
UW Medicine physicians are helping conduct a study to see whether nerve stimulation can reduce the inflammation that causes rheumatoid arthritis. This is the first large-scale trial to see if manipulating the nervous system can influence the immune system. The study reflects a growing interest in the use of electrical devices — so-called electroceuticals —...
Rheumatoid arthritis (RA) is an autoimmune condition, meaning the immune system mistakenly attacks healthy tissues. RA in the knees may severely affect a person’s mobility. RA commonly affects the joints in the hands, wrists, and knees, causing the lining of the joints to become inflamed and damaged. RA is typically symmetrical, affecting both sides of...
Senescent cell accumulation is a feature of aging, a growing imbalance between the rate of creation and rate of destruction. Senescent cells perform a number of useful tasks in the short-term, but when present for the long-term, their inflammatory secretions disrupt tissue function and contribute meaningfully to the onset and progression of age-related disease. A great many research...
OCTOBER 27TH, 2021, CONN HASTINGS Scientists at MIT announced the development of a rapid COVID-19 test that can detect the virus in a saliva sample in as little as five minutes. The technology does not require antibodies or other expensive reagents typically associated with protein detection, and is instead based on carbon nanotubes. The nano-structures...
MEDICAL COLLEGE OF GEORGIA AT AUGUSTA UNIVERSITY IMAGE: DR. RAVINDRA KOLHE CREDIT: MICHAEL HOLAHAN, AUGUSTA UNIVERSITY AUGUSTA, Ga. (Nov. 1, 2021) – With mask wearing and social distancing on the decline and the cold and flu season upon us, researchers have developed a viral panel that enables the simultaneous testing for SARS-CoV-2 along with numerous common respiratory...
KAZAN FEDERAL UNIVERSITY IMAGE: STRUCTURE OF THE STUDIED COMPOUNDS CREDIT: KAZAN FEDERAL UNIVERSITY Over the last few decades, the number of patients suffering from various forms of mycoses has noticeably increased. Currently, the more than 2.5 million people are suffering from superficial mycoses of the skin in the world annually, and their share in the...
by University of Saskatchewan Dr. Michael Levin and his research team are looking for new ways to treat multiple sclerosis by examining how nerve signals become compromised. Credit: University of Saskatchewan Research from a University of Saskatchewan (USask) College of Medicine team will help develop medications that can inhibit the nerve cell damage that occurs...
by Newcastle University Fig. 1: Manhattan plots from acute myeloid leukemia meta-analysis of 4 genome-wide association studies. For each GWAS, association tests were performed for all AML cases and cytogenetically normal AML assuming an additive genetic model, with nominally significant principal components included in the analysis as covariates. Association summary statistics were combined for variants...
UNIVERSITY OF SOUTH AUSTRALIA IMAGE: 5:2 DIET IS JUST AS EFFECTIVE AT ACHIEVING WEIGHT LOSS AS A CONTINUOUS ENERGY-RESTRICTED DIET. CREDIT: ANNA PELZER – UNSPLASH Weight loss after gestational diabetes can prevent the onset of type 2 diabetes. Yet finding the most effective way to lose weight and keep it off can be a challenge, especially for mothers...
