by Max Planck Society Masks that do not fit tightly at the edges allow air to enter and exit, especially at the nostrils, but also at the cheeks. But even ill-fitting masks still significantly reduce the risk of infection. Credit: Birte Thiede/MPI für Dynamik und Selbstorganisation Three meters are not enough to ensure protection. Even at...
Study finds daytime meals may reduce health risks linked to night shift work
by NIH/National Heart, Lung and Blood Institute Credit: CC0 Public Domain A small clinical trial supported by the National Institutes of Health has found that eating during the nighttime—like many shift workers do—can increase glucose levels, while eating only during the daytime might prevent the higher glucose levels now linked with a nocturnal work life. The...
Changing the identity of cancer cells to eliminate them
In the late 1980s, scientists developed a revolutionary approach to treating acute myeloid leukemia (AML), a type of blood cancer. Called differentiation therapy, it amounted to a bona fide cure for many patients. The treatment works by triggering cells “stuck” with a cancerous identity to keep developing and maturing, giving rise to different, non-disease causing...
Mouse study suggests manipulation of certain nerve cells can help regenerate lost heart muscle
JOHNS HOPKINS MEDICINE IMAGE: THIS IMAGE ILLUSTRATES THE NOVEL ROLE OF HEART NERVES IN POSTNATAL HEARTS WHERE SYMPATHETIC NEURONS INFLUENCE CLOCK GENES TO REGULATE CELL CYCLE PROGRESSION OF HEART MUSCLE CELLS. CREDIT: PHOTO COURTESY OF EMMANOUIL TAMPAKAKIS Human heart muscle cells cease to multiply after birth, making any heart injury later in life a permanent...
Stroke drug shows promise in treating Alzheimer’s and dementia
by University of Southern California Credit: Pixabay/CC0 Public Domain A human stroke drug, fast-tracked by the Food and Drug Administration and soon entering Phase 3 clinical trials, shows intriguing signs that it might also be a safe and powerful defense against Alzheimer’s and other forms of dementia. A new study published Tuesday in the Journal of Experimental...
Study: How to freeze-dry a potential COVID-19 vaccine
by University at Buffalo The freeze-dried ingredients of a liposome-based vaccine that could be developed for COVID-19. Credit: Douglas Levere / University at Buffalo Things that are freeze-dried: Astronaut food. Emergency rations. And, just maybe, some future COVID-19 vaccines. Freeze-drying is a method for removing water from a product. First, you freeze the item you’re trying...
Combat stress: A fact of life for T cells fighting cancer or viral infections
by Delthia Ricks , Medical Xpress Characterization of WT and PD-1-/- memory CD8 T cells following rapamycin treatment. Equal numbers of WT and PD-1-/- P14 CD8 T cells were adoptively co-transferred at a high dose (5×104 cells) into C57BL/6 mice. Mice were infected with LCMVArm and remained untreated (UnTx) or were treated (Tx) with rapamycin daily following...
New research uncovers mercury’s long-term health effects
by Mark Michaud, University of Rochester Medical Center Methylmercury (MeHg) is a well-known neurotoxin that can impact brain development, particularly in utero. A series of new studies from researchers at the University of Rochester Medical Center (URMC) indicate that exposure may disrupt the early development of the connections between muscles and the brain, which could lead...
Scientists solve an important part of the mystery of ultra-rare blood clots linked to adenovirus-based COVID-19 vaccines
by Arizona State University A cloud of platelet factor 4 proteins interacting with the electrostatic surface of the Oxford vaccine, as seen through the computational microscope. Credit: Chun Kit Chan, Arizona State University An international team of scientists believe they may have found a molecular mechanism behind the extremely rare blood clots linked to adenovirus COVID-19...
Researchers carry out the first head-to-head comparison of the Pfizer and Moderna vaccines
by Tamar Nordenberg, Veterans Affairs Research Communications Credit: Pixabay/CC0 Public Domain In the first head-to-head comparison of the effectiveness of the Pfizer-BioNTech and Moderna COVID-19 vaccines, researchers examined the electronic health records of veterans who had received each vaccine. Both vaccines were highly effective in preventing COVID-19 outcomes such as documented infection, hospitalization, and death....