by University of New South Wales Credit: Pixabay/CC0 Public Domain Research led by UNSW Sydney’s Center for Healthy Brain Aging (CHeBA) has confirmed treating symptoms of depression is most effective when a non-pharmacological approach is adopted, in people living with dementia. Depression is a common psychological symptom associated with dementia and is estimated to occur...
by Jacqueline Mitchell, Beth Israel Deaconess Medical Center Omicron Subvariant Mutations and Neutralizing Antibody Responses. Panel A shows the lineage of mutations that have been identified in the omicron BA.1, BA.2, BA.2.12.1, and BA.4 or BA.5 subvariants of SARS-CoV-2, as compared with the reference WA1/2020 isolate. BA.4 and BA.5 have identical sequences of the spike protein...
by Nancy Fliesler, Children’s Hospital Boston Graphical abstract. Credit: Cell Reports (2022). DOI: 10.1016/j.celrep.2022.110662 Many serious pulmonary diseases, including genetic lung diseases, lack an effective treatment other than the most extreme: lung transplant. A team at Boston Children’s Hospital envisions a much better option: cell therapy, using lung stem cells created from patients’ own cells to repair...
by The Ohio State University Credit: Unsplash/CC0 Public Domain Researchers at The Ohio State University Wexner Medical Center and College of Medicine have developed a novel drug molecule that targets T-cells causing inflammation in heart failure patients, stopping further progression of the disease. During heart failure, T-cells, which are part of the immune system, go from...
by Thomas Jefferson University Credit: Pixabay/CC0 Public Domain Colorectal, pancreatic, esophageal and stomach cancers—some of the deadliest kinds of cancer—have high recurrence rates where the cancer comes back even after successful surgery or radiation treatment. To combat these treatment-resistant cancers, Thomas University Jefferson researchers led by Adam Snook, Ph.D., an associate professor of pharmacology and...
by Martin Lasalle, University of Montreal Credit: Unsplash/CC0 Public Domain Without realizing it, we all rely on emotional regulation many times a day. It’s the process by which we mitigate the effect of disturbing stimuli in order to stay focused, improve our well-being and respond to demands from our environment. Emotional regulation plays a key role...
UNIVERSITY OF SOUTHERN DENMARK IMAGE: LAB WORK AT UNIVERSITY OF SOUTHERN DENMARK CREDIT: EMIL RYGE/UNIVERSITY OF SOUTHERN DENMARK Antibiotic resistance is a ticking bomb under public health. WHO predicts that in 2050 more people will die from infections than from cancer – and we are talking about infections that we today consider harmless; infections that...
by Vanderbilt University Medical Center Credit: Pixabay/CC0 Public Domain Patients whose race is recorded as Black in their electronic health record (EHR) are more likely to have azathioprine, an immunosuppressant medication, discontinued or its dose reduced because their laboratory results show a low white blood cell count. This lab finding was not a factor of...
INTERNATIONAL ASSOCIATION FOR THE STUDY OF LUNG CANCER (Denver—9 a.m. EDT–June 22, 2022)—Cancer patients have received priority status to receive COVID-19 vaccinations but there is limited data regarding the safety and efficacy of the vaccines for patients treated for lung cancer with immune checkpoint inhibitors. Now, a new study published in the Journal of Thoracic Oncology found...
by Walter and Eliza Hall Institute of Medical Research Learning the rules for programming self-associating membrane proteins (MPs). (a) Rosetta fold, dock, and design uses backbone fragments from natural MPs to construct symmetric, de novo architectures and an MP energy function (Weinstein et al., 2019) to optimize the amino acid sequence. (b) Round 1 designs...
