by University of California – Riverside Participants at the UCR Brain Game Center play a working memory training game. Credit: Audrey Carrillo, Brain Game Center, UC Riverside. If you are skilled at playing puzzles on your smartphone or tablet, what does it say about how fast you learn new puzzles, or, more broadly, how well...
Venom from deadliest snakes could stop uncontrolled bleeding
by University of Queensland Schematic overview of the mechanism of action of the implemented snake venom proteins. Ecarin, a procoagulant snake venom protein bypasses the activation of series of clotting factors via intrinsic and extrinsic clotting pathway and directly activates prothrombin to thrombin thereby producing a fibrin blood clot. Once the clot is formed, clot...
US death rate from alcoholic liver cirrhosis triples over two decades
by Steven Reinberg Americans may have a collective drinking problem, made worse by the obesity epidemic, new research suggests. The new study found that deaths from alcoholic cirrhosis have more than tripled in 20 years. In 1999, alcoholic cirrhosis—an advanced form of alcohol-related liver disease—killed just over 6,000 Americans (a rate of 3 per 100,000). By 2019,...
Protein changes in cerebrospinal fluid indicate inflammatory processes in the brain
by Universitaet Tübingen Credit: Pixabay/CC0 Public Domain Alzheimer’s, Parkinson’s and other neurodegenerative diseases are associated with inflammatory processes in the brain. German researchers have succeeded in identifying a group of proteins in cerebrospinal fluid that could provide information about such inflammatory processes. As so-called biomarkers, the proteins could help researchers to better understand disease processes in...
New blood biomarker identified for status of fatty liver disease
by Johannes Angerer, Medical University of Vienna Graphical abstract. Credit: Journal of Hepatology (2022). DOI: 10.1016/j.jhep.2022.06.004 A MedUni Vienna study team has identified the role of a specific subtype of macrophages (white blood cells) in progressive non-alcoholic fatty liver disease. As part of the immune system, these cells have a protective function against fibrosis and liver cirrhosis. At...
Study uncovers new treatment approaches for liver cancer patients
by Cara Martinez, Cedars-Sinai Medical Center Credit: Pixabay/CC0 Public Domain Experts from Cedars-Sinai Cancer have analyzed patient samples, along with studies conducted in animal models, to identify a novel immune checkpoint pathway to treat hepatocellular carcinoma, the most common form of liver cancer. This big data analysis, coupled with existing immune boosting therapies, provides a...
Study shows inhaled toxic particles take direct route from lungs to brain
by University of Birmingham Credit: Pixabay/CC0 Public Domain Breathing in polluted air could lead to toxic particles being transported from lungs to brain, via the bloodstream—potentially contributing to brain disorders and neurological damage, a new study reveals. Scientists have discovered a possible direct pathway used by various inhaled fine particles through blood circulation with indications...
Monkeypox: Normal precautions, but no special precautions, are needed to combat virus, advises expert
by Rutgers University-New Brunswick Credit: Pixabay/CC0 Public Domain David J. Cennimo, an associate professor of medicine and pediatrics in the Division of Infectious Diseases at Rutgers New Jersey Medical School, says there’s no need for people to take special steps to avoid monkeypox. Cennimo, who believes that precautions already recommended to prevent other illnesses are enough to...
Novel in-situ microwave hyperthermia therapy to overcome multidrug-resistant E. coli infections
by The University of Hong Kong Treatment efficacy:Urinary tract infection: a) Thermal images indicating the skin temperature over the bladder after injection with saline, PLGA microparticles (MPs), and gentamicin-loaded PLGA MPs (Gen-PLGA MPs), and microwave hyperthermal (MWH) irradiation for 10 minutes. b–d) MDR E. coli bacterial burden in b) urine, c) the bladders, and d)...
Lab-grown fat cells help scientists understand type 2 diabetes
by Eva Frederick, Whitehead Institute for Biomedical Research Lab-grown adipocyte with nuclei in blue, green being Cellmask staining the whole cell membrane, and in red the distinguishing features of adipocytes—lipid droplets—stained with Lipidtox. Credit: Max Friesen In research published June 17 in the journal Science Advances, researchers in the lab of Whitehead Institute Founding Member Rudolf Jaenisch...