Michael Marshall After a COVID-19 infection, some people have recovered their ability to perceive odours thanks to smell training. Credit: Fabio Bucciarelli/The New York Times/eyevine Researchers are finally making headway in understanding how the SARS-CoV-2 coronavirus causes loss of smell. And a multitude of potential treatments to tackle the condition are undergoing clinical trials, including...
Electronic nose detects SARS-CoV-2 from breath
By Dr. Priyom Bose, Ph.D. Jun 8 2022 Reviewed by Benedette Cuffari, M.Sc. Early diagnosis of infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of the coronavirus disease 2019 (COVID-19) pandemic, is important to restrict its transmission. In this context, a reliable point-of-care testing system is urgently needed. Some of the...
Disclosure of the mechanism that regulates the resolution of inflammation
INSTITUTE FOR RESEARCH IN BIOMEDICINE (IRB BARCELONA) IMAGE: DURING THE INFLAMMATORY PHASE, INFLAMMATORY MARKERS (IN GREEN) ARE LOCALIZED IN THE MACROPHAGES NUCLEUS (IN BLUE) TO ACTIVATE THE SYNTHESIS OF INFLAMMATORY ARNS. CREDIT: IRB BARCELONA Inflammation is a temporary reaction to infection or injury that is intended to attract cells of the immune system so they...
Maintaining the right niche for blood cell development
OSAKA UNIVERSITY IMAGE: RUNX1/2 INHIBIT FIBROTIC CONVERSION OF CAR CELLS CREDIT: 2022 YOSHIKI OMATSU ET AL. RUNX1 AND RUNX2 INHIBIT FIBROTIC CONVERSION OF CELLULAR NICHES FOR HEMATOPOIETIC STEM CELLS. NATURE COMMUNICATIONS. USED UNDER CC BY (HTTPS://CREATIVECOMMONS.ORG/LICENSES/BY/4.0/). ONLY TEXT IN THE FIGURE WAS CHANGED FROM ORIGINAL. Osaka, Japan – In your home, storing books on a...
Novel brain-permeable BRAF inhibitor shows promise in more effectively reaching and treating melanoma brain metastasis
VALL D’HEBRON INSTITUTE OF ONCOLOGY IMAGE: JOAN SEOANE, CO-DIRECTOR OF PRECLINICAL AND TRANSLATIONAL RESEARCH AT THE VALL D’HEBRON INSTITUTE OF ONCOLOGY (VHIO). CREDIT: VALL D’HEBRON INSTITUTE OF ONCOLOGY (VHIO). Published in Cancer Research, findings reveal the potent and prolonged antitumor activity of C1a in patient-derived preclinical models of mutant-BRAF-driven melanoma brain metastases, even upon relapse on...
Good bacteria to tackle depression
UNIVERSITY OF BASEL Intestinal flora plays an important role in health – including mental health. Researchers from the University of Basel and the University Psychiatric Clinics Basel (UPK) have shown that probiotics can support the effect of antidepressants and help to alleviate depression. When he was visited by what he called “the black dog”, Winston...
Chung-Ang University researchers use biomolecule-loaded metal-organic frameworks nanopatterns to aid artificial stem cell differentiation
CHUNG ANG UNIVERSITY IMAGE: RESEARCHERS FROM KOREA HAVE DEVELOPED A NOVEL PLATFORM THAT PROMOTES HIGHLY EFFICIENT STEM CELL DIFFERENTIATION OUTSIDE THE BODY USING METAL-ORGANIC FRAMEWORK NANOPARTICLE – EMBEDDED IN NANOPIT ARRAYS. THIS COULD OPEN DOORS TO TREATMENT OF NEUROLOGIC DISORDERS SUCH AS ALZHEIMER’S AND PARKINSON’S DISEASES. CREDIT: CODONAUG FROM OPENVERSE Stem cells are essentially our...
Heart failure patients unvaccinated against COVID-19 are three times more likely to die from it than boosted heart failure patients
THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE Heart failure patients who are unvaccinated against SARS-CoV-2, the virus that causes COVID-19, are three times more likely to die if infected with the virus compared to fully boosted heart failure patients, according to new research out of Mount Sinai Heart. The study, published June...
New screening test for those at risk of sudden cardiac arrest
VICTOR CHANG CARDIAC RESEARCH INSTITUTE IMAGE: PROFESSOR JAMIE VANDENBERG OPERATING THE SYNCROPATCH AT THE VICTOR CHANG CARDIAC RESEARCH INSTITUTE CREDIT: VICTOR CHANG CARDIAC RESEARCH INSTITUTE New research from the Victor Chang Cardiac Research Institute will allow families around the world to discover if they are carrying genetic mutations that cause sudden cardiac arrest – a...
Genetic study offers new insights into DCIS biology, progression
UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER HOUSTON ― A new study led by the global Cancer Grand Challenges PRECISION team, including researchers from The University of Texas MD Anderson Cancer Center, shifts the long-held belief that all invasive breast cancers following ductal carcinoma in situ (DCIS) arise from the original DCIS lesion. The results, published today in Nature Genetics, demonstrate that...