by University of Geneva Killer-T cells (green) attack lymphatic vessels (red) in tumours and induce their death (cell death marker in white). Credit: UNIGE – Robert Pick / Stéphanie Hugues To grow, tumors rely on a specific structure, the tumor stroma. This includes blood vessels, which provide the nutrients necessary for the multiplication of diseased...
Higher fish consumption may be associated with increased melanoma risk: study
by Springer Credit: Pixabay/CC0 Public Domain Eating higher levels of fish, including tuna and non-fried fish, appears to be associated with a greater risk of malignant melanoma, suggests a large study of US adults published in Cancer Causes & Control. Eunyoung Cho, the corresponding author said: “Melanoma is the fifth most common cancer in the U.S....
Investigators discover a ‘double life’ for a key Parkinson’s disease protein
by Brigham and Women’s Hospital A graphic depicts the “two faces of alpha-synuclein” and the transition from normal states (upper, organized molecular machines on a well-defined grid) to pathologic states in which there is membrane disruption, altered protein interactions and localization (lower, chaotic, disrupted machines, darker tone). Credit: Gergana Petrova. One of the hallmarks of...
First patient receives Moderna mRNA trial infusion for glycogen storage disease
by Jennifer Walker, University of Connecticut Love Joy, a nurse at UConn Health takes Loveah Hernandez’s blood pressure. Credit: Shaylee King Prior to COVID-19 vaccines most people had never heard of messenger RNA (mRNA) used to create two of the COVID-19 vaccines on the market. However, mRNA was discovered in 1960 and since that time...
Findings from a prospective phase II study with dostarlimab for advanced local rectal cancer
by European Society for Medical Oncology Credit: Unsplash/CC0 Public Domain In a prospective phase II study that involved patients with mismatch repair–deficient locally advanced rectal cancer, treatment with neoadjuvant single-agent, PD1 inhibitor dostarlimab resulted in a clinical complete response—as measured by the combination of rectal MRI, visual endoscopic inspection, and digital rectal examination—in all included...
How to Lower Blood Sugar Quickly
BY AMY CAMPBELL, MS, RD, LDN, CDCES | JUNE 1, 2022 High blood sugar, also called hyperglycemia, means that there is too much glucose (sugar) in the blood, often due to a lack of insulin or the body’s inability to use insulin properly. For people who have diabetes, other factors can contribute to high blood sugars, as well,...
Yes, women might ‘feel the cold’ more than men. Here’s why biological sciences
by Charlotte Phelps and Christian Moro, The Conversation Credit: Shutterstock We all have different preferences for when it’s the right time to bring out the winter blankets. And the thermostat’s setting often forms the basis of office arguments between women and men regarding the “correct” temperature for it to be set. Between the sexes, there are always...
Causes of Liver Cancer are Changing Around the World: Some Up, Some Down
The primary causes of liver cancer are well known: viral (hepatitis B and C), alcohol, and non-alcoholic steatohepatitis (NASH), a condition in which fat builds up in the liver, resulting in chronic inflammation and damage. But in a paper published in Cell Metabolism, an international team of scientists, led by researchers at the University of California San Diego...
Adult survivors of childhood cancer often undertreated for cardiovascular risk factors
AMERICAN HEART ASSOCIATION Embargoed until 4 a.m. CT/5 a.m. ET Wednesday, June 8, 2022 DALLAS, June 8, 2022 — Adults who survive childhood cancer have a higher risk of cardiovascular disease than the general population, yet they are 80% more likely to be undertreated for several cardiovascular risk factors: hypertension (also called high blood pressure),...
Zinc found to play an important role in lung fibrosis
CEDARS-SINAI MEDICAL CENTER Investigators from the Women’s Guild Lung Institute at Cedars-Sinai have discovered that zinc, a common mineral, may reverse lung damage and improve survival for patients with a deadly age-related condition known as idiopathic pulmonary fibrosis (IPF). Their findings, published in The Journal of Clinical Investigation, have the potential to change the landscape of treatment for...