by Joel Streed, Mayo Clinic Credit: Pixabay/CC0 Public Domain Simply put, pancreatitis is inflammation of the pancreas. Located behind the stomach in the upper abdomen, your pancreas produces digestive enzymes and hormones that regulate how your body produces sugar. Pancreatitis is caused by the irritation and inflammation of the cells of your pancreas. This occurs when digestive enzymes released...
New drug candidate developed to treat type 2 diabetes
by Birgit Niesing, Deutsches Zentrum für Diabetesforschung GLP-1RA/tesaglitazar in obese GLP-1R knockout mice. a–n, Body weight (a,h), change in fat and lean tissue mass (b,c,i,j), cumulative food intake (d,k), blood glucose (e,l) and i.p. GTT (f,m) in 36-week-old male DIO wildtype (WT) (a–g) or GLP-1R knockout (KO) mice (h–n) treated for 6 days with either vehicle...
Some cancer immunotherapy treatments may damage fertility
by Monash University Credit: Pixabay/CC0 Public Domain Researchers have discovered that some immunotherapy treatments used to treat cancer can cause fertility damage. It means these treatments could affect the future fertility and hormonal health of female cancer survivors, prompting experts to call for more research and preventative measures, such as freezing eggs. Led by the Biomedicine...
New gene therapy shows promise for treating age related macular degeneration
by Trinity College Dublin Rescue of ARPE19 cells insulted with NaIO3. 5.0 × 104 ARPE19 cells were transduced with AAV2/8-ophNdi1 5-h post-seeding; MOI = 5.4 × 105 (K–O). Twenty-eight-hour post-transduction cells were insulted with 5-mM NaIO3 (F–O) and 24-h post-insult cells were fixed and stained with Phalloidin-iFluor 647 (F-actin, light blue), and CPN60 (mitochondrial marker, magenta) and 8-OHdG-Alexa Fluor 488 (oxidative stress marker, green) immunocytochemistries;...
Feeling anxious or blue? Ultra-processed foods may be to blame
by Florida Atlantic University More than 70 percent of packaged foods in the U.S. are classified as ultra-processed food and represent about 60 percent of all calories consumed by Americans. Credit: Florida Atlantic University Do you love those sugary-sweet beverages, reconstituted meat products and packaged snacks? You may want to reconsider based on a new study...
New data shows COVID-19 vaccine does not raise stroke risk
by Cedars-Sinai Medical Center Credit: Cedars-Sinai Newly compiled data evaluated by researchers in the Department of Neurology and the Smidt Heart Institute at Cedars-Sinai shows that COVID-19 vaccines do not raise stroke risk—but that severe COVID-19 infection does. Physician-scientists hope this growing body of evidence, highlighted today in an editorial in the journal Neurology, will ease the...
Does your loved one have an eating disorder? Look for these 7 signs
Roughly 30 million Americans have an eating disorder in their lifetime, and calls to a nationwide support group have surged during the COVID-19 pandemic. Between March 2020 and October 2021, the National Eating Disorders Association (NEDA) recorded a 58% increase in calls, texts and emails seeking help. Behind opioid addiction, eating disorders have the second highest risk of death of...
Higher-weight people and eating disorders
by La Trobe University Credit: Unsplash/CC0 Public Domain National guidelines have been released for the first time to help health professionals better support people with higher weight and living with eating disorders. Developed by eating disorder experts including researchers, clinicians and people with lived experience, in partnership with the National Eating Disorders Collaboration, the guidelines were published...
Low job control a risk factor for suicidal behavior
by Swedish Research Council Credit: Pixabay/CC0 Public Domain Men working in occupations featuring low demands and low control over their own work situation are at elevated risk for suicide attempts and suicide. In jobs with high demands and high control, the risk is lower. This is shown in a study from the University of Gothenburg. Men...
Population-based study: Autoimmune disorders increase risk of cardiovascular disease
by KU Leuven Credit: Pixabay/CC0 Public Domain About 10% of the population in high income regions like Europe and the United States has been diagnosed with one or multiple autoimmune disorders. Examples are rheumatoid arthritis, psoriasis, systemic sclerosis, lupus erythematosus and type I diabetes. Although earlier research has suggested associations between some of these disorders...