Month: <span>January 2023</span>

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Atrial Failure or Insufficiency: A New Syndrome

Matías A. Loewy January 13, 2023 Atrial dysfunction, widely considered a marker or consequence of other heart diseases, is a relevant clinical entity, which is why it is justified to define atrial failure or insufficiency as “a new syndrome that all cardiologists should be aware of,” said Adrián Baranchuk, MD, PhD, professor of medicine at Queen’s University,...

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Oral Anticoagulant Mistakes to Avoid in Older Adults With AF

Mauricio Wajngarten, MD December 23, 2022 The relevance of oral anticoagulants (OACs) for older adults with atrial fibrillation (AF) does not need to be reiterated. It has been posited that the availability of direct oral anticoagulants (DOACs) would substantially increase the prevention of thromboembolic events in older adults with AF, given the superior safety profile of these agents and...

The link between mental health and ADHD is strong—so why aren’t we paying attention?
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The link between mental health and ADHD is strong—so why aren’t we paying attention?

by University of Bath Credit: Pixabay/CC0 Public Domain Adults with high levels of attention-deficit hyperactivity disorder (ADHD) symptoms are more likely to experience anxiety and depression than adults with high levels of autistic traits, according to new research led by psychologists at the University of Bath in the UK. This study is the first to...

Scientists find mechanical stimulation could be used to prevent falls and strengthen muscles
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Scientists find mechanical stimulation could be used to prevent falls and strengthen muscles

by Aston University Corticomuscular coherence topographic maps and spectra. On the left-side, voltage topographic maps of the difference between EMG-EEG couplings before and EMG-EEG couplings after the WBVs (CMCBB and CMCPSB, respectively), averaged across subjects, are reported for the right GL (a.1) and the right SOL (a.2). The asterisks depict electrodes that showed a significantly bigger...

New drug candidate slows the progression of adrenoleukodystrophy
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New drug candidate slows the progression of adrenoleukodystrophy

by Paris Brain Institute Credit: Pixabay/CC0 Public Domain The work of Professor Fanny Mochel (AP-HP, Sorbonne University) at Paris Brain Institute, in collaboration with clinical research teams in eight countries and Spanish biotech Minoryx Therapeutics, has demonstrated the protective effects of leriglitazone in the progression of adrenoleukodystrophy—a rare genetic disease in which the white matter of the central...

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IMPLANT THAT TURNS THOUGHT INTO ACTION APPEARS SAFE IN TRIAL

More than two decades ago, a team researchers set out with an ambitious goal to provide people with paralysis a revolutionary neurotechnology capable of turning thoughts about movement into actual action, using a tiny device that would one day be implanted in the surface of the brain. Their work led to an ongoing effort to create the BrainGate brain-computer...

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Is Stem-Cell Therapy the Ultimate Treatment for Brain Diseases like Alzheimer’s and Autism?

Over the last decade, you have probably heard about stem cell research on the news or online. You are probably wondering what exactly stem cells are and why they are such a popular subject for debate. In recent years, scientists and medical institutions have been studying many ways stem cell therapy can treat various diseases. Notably, in the field...

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Defects in mitotic and telomere function increase risk for sarcomas

AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE (AAAS) Heritable pathogenic defects in genes related to mitosis and telomere function may specifically increase the risk for sarcomas – rare cancers that develop in muscles, bones, and other connective tissues, researchers report. The findings provide new biological insight into sarcoma development and could inform better genetic risk profiles for...

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A blood test for cancer shows promise thanks to machine learning

UNIVERSITY OF WISCONSIN-MADISON A team of researchers at the University of Wisconsin­–Madison have successfully combined genomics and machine learning in the quest to develop accessible tests that allow earlier detection of cancer. In a study published this week in Science Translational Medicine and led by Muhammed Murtaza, professor of surgery at the UW School of Medicine and Public Health, researchers used a...

Expanding gene therapy for rare disease that causes blindness
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Expanding gene therapy for rare disease that causes blindness

UNIVERSITY OF HOUSTON IMAGE: MUNA NAASH, UNIVERSITY OF HOUSTON JOHN S. DUNN ENDOWED PROFESSOR OF BIOMEDICAL ENGINEERING, IS EXPANDING A METHOD OF GENE THERAPY WITH THE HOPES IT WILL RESTORE VISION LOSS IN USHER SYNDROME TYPE 2A. CREDIT: UNIVERSITY OF HOUSTON A University of Houston researcher is expanding a method of gene therapy with the...