UNIVERSITY OF COLORADO AT BOULDER Engineers at the University of Colorado Boulder are tapping into advances in artificial intelligence to develop a new kind of walking stick for people who are blind or visually impaired. Think of it as assistive technology meets Silicon Valley. The researchers say that their “smart” walking stick could one day help blind...
Month: <span>January 2023</span>
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UCLA chemists are first to synthesize ocean-based molecule that could fight Parkinson’s
UNIVERSITY OF CALIFORNIA – LOS ANGELES Organic chemists at UCLA have created the first synthetic version of a molecule recently discovered in a sea sponge that may have therapeutic benefits for Parkinson’s disease and similar disorders. The molecule, known as lissodendoric acid A, appears to counteract other molecules that can damage DNA, RNA and proteins...
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Investigational drug may combat brain tumors by targeting cancer cells’ fat production
by Katie Marquedant, Massachusetts General Hospital Correlation analysis between SCD expression and sensitivity to YTX-7739. (A) Immunoblot analysis (left) of SCD expression in YTX-7739-sensitive and -resistant GSCs lines. Also shown (right) is the correlation analysis between the EC50 of YTX-7739 and SCD expression in all 12 GSCs lines. Western-blot bands of SCD normalized to GAPDH were...
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Research indicates wider benefit to AstraZeneca vaccine
by Trinity College Dublin Graphical abstract. Credit: Journal of Clinical Investigation (2022). DOI: 10.1172/JCI162581 A review of the COVID-19 vaccine trials indicate that adenovirus vectored vaccines may have non-specific protective effects resulting in significantly reduced all-cause mortality and non-COVID deaths, compared with mRNA based COVID-19 vaccines. The mechanism behind this observation is unknown. New Trinity research has discovered that...
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Scientists find potential cellular target for HIV therapies
by Bill Levesque, University of Florida Credit: Unsplash/CC0 Public Domain Researchers at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology have discovered a protein that appears to play a key role in helping HIV replicate in human immune cells, providing more clues about how cellular machinery allows the virus to create new copies...
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How pancreatic cancer defies treatment by leveraging a protein
by University of California – San Diego Pancreatic cancer cells (nuclei in blue) are shown growing as a sphere encased in membranes (red). Credit: National Cancer Institute Pancreatic cancer is the third deadliest cancer in the United States, after lung and colorectal, though far less common. It is also among the hardest to effectively treat,...
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Regenerative drug restores bone in preclinical study
by Main Line Health Degeneration of the mouse jawbone in the presence of ligature followed by regeneration of the jawbone post-ligature and post-drug. (Aab) The ligature-induced periodontitis model. 5–0 silk suture was passed through the interdentium between the maxillary first molar, the second molar and third molar using Dumont forceps. Suture was tied firmly using...
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Neural prosthesis uses brain activity to decode speech
by Anastasia Lobanova, National Research University Higher School of Economics Credit: Nitish V. Thakor, Science Translational Medicine Researchers from HSE University and the Moscow State University of Medicine and Dentistry have developed a machine learning model that can predict the word about to be uttered by a subject, based on their neural activity recorded with a small set of...
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High frequency brain wave patterns in the motor cortex can predict an upcoming movement
by University of Chicago Medical Center Credit: CC0 Public Domain Nicholas G. Hatsopoulos, Ph.D., Professor of Organismal Biology and Anatomy at the University of Chicago, has long been interested in space. Specifically, the physical space occupied by the brain. “Inside our heads, the brain is all crumpled up. If you flattened out the human cortex...
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Sensing odor molecules on a graphene surface layered with self-assembled peptides
by Tokyo Institute of Technology Credit: Biosensors and Bioelectronics (2022). DOI: 10.1016/j.bios.2022.115047 Graphene-based olfactory sensors that can detect odor molecules based on the design of peptide sequences were recently demonstrated by researchers at Tokyo Tech. The findings indicated that graphene field-effect transistors (GFETs) functionalized with designable peptides can be used to develop electronic devices that mimic olfactory receptors and emulate...