by University of Bristol Potassium isotope compositions of minipig brain regions indicate heavy K isotope enrichment coincident with amyloid beta accumulation, suggesting a mechanistic linkage and potential for downstream signal transferal to blood serum (i.e. noninvasive diagnostic potential). Credit: Metallomics (2022). DOI: 10.1093/mtomcs/mfac090 New research from a James Cook University-led study has proposed a hypothesis that higher levels of...
Increased coffee consumption may reduce severity of non-alcoholic fatty liver disease in those with type 2 diabetes
by University of Coimbra Credit: CC0 Public DomainA new study by the University of Coimbra, published in Nutrients, has revealed that caffeine, polyphenols, and other natural products found in coffee may help reduce the severity of non-alcoholic fatty liver disease (NAFLD) among overweight people with type 2 diabetes (T2D). NAFLD is a collective term for liver disorders...
Mature ‘lab grown’ neurons hold promise for neurodegenerative disease
by Northwestern University Fluorescent images of human neurons (stained with red, green and blue) growing on coatings with fast-moving molecules (left) or conventional laminin (right) for 72 hours. Neurons attached and spread homogenously on the highly mobile coating but remained clumped together on the laminin coating. Credit: Northwestern University Northwestern University-led researchers have created the first highly...
Common brain network for psychiatric illness discovered
by Brigham and Women’s Hospital Credit: Pixabay/CC0 Public Domain Psychiatric illnesses, such as schizophrenia and depression, affect nearly one in five adults in the United States and nearly half of patients diagnosed with a psychiatric illness also meet the criteria for a second. With so much overlap, researchers have begun to suspect that there may be one...
Link between sphingolipids and complement signaling may be key to stopping cancer metastasis
by Caroline Wallace, Medical University of South Carolina Graphical Abstract. Credit: Cell Reports (2022). DOI: 10.1016/j.celrep.2022.111742 MUSC Hollings Cancer Center researchers have identified the sequence of molecular interactions that could be key to stopping the spread of cancer cells. Currently, there is no reliable therapeutic approach to prevent metastasis, the leading cause of death from solid cancerous tumors. Published...
Large clinical trial to test cough medicine as Parkinson’s treatment
By Rich Haridy January 11, 2023 Ambroxol, an ingredient in common cough medicines, may be useful in treating Parkinson’s disease Depositphotos A landmark Phase 3 clinical trial is beginning in the UK, testing whether a common cough medicine can be used to treat Parkinson’s disease. Early studies indicate the 50-year-old drug can cross into the...
Nanotechnology may improve gene therapy for blindness
by Oregon Health & Science University Oregon Health & Science University and Oregon State University researchers are developing a new approach to deliver gene therapy to address blindness-causing genetic mutations. Their new method encases gene-editing molecules inside a shell of lipid nanoparticles. This scientific illustration shows the approach’s lipid nanoparticle shells, which appear as fuzzy beige balls after...
Artificial pancreas successfully trialed for use by type 2 diabetes patients
by University of Cambridge Credit: Pixabay/CC0 Public Domain Cambridge scientists have successfully trialed an artificial pancreas for use by patients living with type 2 diabetes. The device—powered by an algorithm developed at the University of Cambridge—doubled the amount of time patients were in the target range for glucose compared to standard treatment and halved the time...
Study unveils similarities in the activity patterns of artificial agents and the brain
by Ingrid Fadelli, Medical Xpress Hierarchical behavior composition in mice. Credit: Hiroshi Makino.Artificial intelligence (AI) draws inspiration from current knowledge of the human brain, artificially replicating some of its learning processes and functions. The extent to which artificial agents successfully emulate the brain’s activity, however, is not yet fully understood. Hiroshi Makino, a researcher at...
A deep belief neural network based on silicon memristive synapses
by Ingrid Fadelli, Tech Xplore Memristors measured in a probe station. Credit: Technion Spokesperson Department. While artificial intelligence (AI) models are becoming increasingly advanced, training and running these models on conventional computer hardware is very energy consuming. Engineers worldwide have thus been trying to create alternative, brain-inspired hardware that could better support the high computational...