Stem cell research may take scientists one step closer to undoing the damage caused by neurodegenerative eye conditions, such as glaucoma. Image credit: Phoebe Jane Barrett/EyeEm/Getty Images. Transplantation of retinal neurons derived from stem cells is a promising approach for the treatment of degenerative conditions of the retina that involve the loss of neurons. The...
BY TIM NEWCOMB PUBLISHED: JAN 10, 2023 Olena Kurashova//Getty Images The concept of reprogramming genes has been buzzworthy in scientific circles for over a decade. A San Diego biotech company now claims it extended the life of mice 7 percent longer with gene reprogramming. Gene reprogramming is ripe for inviting cancer. Scientists just extended the life of mice 7...
by Ecole Polytechnique Federale de Lausanne A schematic summary of the study. Credit: Douglas Hanahan (EPFL) Immunotherapy is a way of treating cancer by reprogramming the patient’s immune system to attack their tumor. This cutting-edge approach has significantly impacted the treatment of cancer patients, and already boasts cases of long-term remission. Nonetheless, many patients either...
by Bruce Goldman, Stanford University Graphical abstract. Credit: Cell (2022). DOI: 10.1016/j.cell.2022.11.030 Somebody just coughed on you. On a plane. At a dinner party. In a supermarket line. If only there were a “morning after” nasal spray that could knock out respiratory viruses’ ability to colonize your nose and throat. In a study published January 5 in...
by David McFadden, University of Ottawa A3-mediated restriction of HIV-1 integration. A Western blot analysis of virus producer cells. HIV-1 pseudotyped virus was produced in 293 T cells by co-transfection of plasmids coding for NL4-3-ΔEnv/ΔVif/eGFP, VSV-G, and either empty pcDNA 3 plasmid (HIV-1 no A3), or each of the A3 expression plasmids. The Control lane is the transfection...
by Yale University BOLD fMRI signals associated with SWDs in GAERS resemble human absence epilepsy. a Statistical Parametric Mapping (SPM) analysis of spike-wave discharge (SWD)-associated changes in blood-oxygen-level-dependent (BOLD) signal. Cortex shows mainly functional magnetic resonance imaging (fMRI) decreases (cool colors), whereas the thalamus shows fMRI increases (warm colors). Values on both color scales indicate the magnitude...
by Johns Hopkins University Bloomberg School of Public Health Credit: Pixabay/CC0 Public Domain A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health found that older adults with greater severity of hearing loss were more likely to have dementia, but the likelihood of dementia was lower among hearing aid users compared to...
by Weill Cornell Medical College Cancer cell experiencing endoplasmic reticulum stress. Credit: Ella Marushchenko (2018) A protein commonly found at high levels in lung cancer cells controls a major immunosuppressive pathway that allows lung tumors to evade immune attack, according to a study led by researchers at Weill Cornell Medicine. The discovery could hasten the development of...
by Valerie Goodwin, University of Michigan Credit: Unsplash/CC0 Public Domain A Michigan Medicine study has identified a new potential target for treating osteoarthritis—a debilitating joint disease that affects over 31 million Americans and is a leading cause of disability worldwide. A team of researchers led by Tristan Maerz, Ph.D., a biomedical engineer and assistant professor in the...
by Wiley Schematic illustration for fabrication of EMVEG using a EG extrusion method. Credit: Advanced Materials Interfaces (2023). DOI: 10.1002/admi.202202255 A product of a freshwater single-celled green algae called Euglena gracilis may enhance skin regeneration to speed up wound healing, according to new research published in Advanced Materials Interfaces. Investigators developed a system based on microvesicles that bud from the...
