Month: <span>January 2023</span>

Home / 2023 / January
Blood pressure drug holds promise for treating PTSD
Post

Blood pressure drug holds promise for treating PTSD

by Medical College of Georgia at Augusta University Dr. Qin Wang and research scientist Hasib Rehman. Credit: Michael Holahan, Augusta University There is new evidence that a 50-year-old blood pressure drug could find new purpose as a treatment to mitigate the often life-altering effects of increasingly prevalent PTSD, scientists say. Clonidine is commonly used as a high...

Drug can spur liver regeneration in Alagille syndrome
Post

Drug can spur liver regeneration in Alagille syndrome

by Sanford Burnham Prebys Medical Discovery Institute Duc Dong, Ph.D. Credit: Sanford Burnham Prebys Research led by Associate Professor Duc Dong, Ph.D., has shown for the first time that the effects of Alagille syndrome, an incurable genetic disorder that affects the liver, could be reversed with a single drug. The study, published in the Proceedings of the...

Dawn-to-dusk dry fasting leads to health benefits in the study of immune cells
Post

Dawn-to-dusk dry fasting leads to health benefits in the study of immune cells

by Baylor College of Medicine Credit: Unsplash/CC0 Public Domain Researchers at Baylor College of Medicine have found more evidence that dry fasting (fasting without food or liquid intake) from dawn to dusk can play an important role in overall health. In a new study published in Metabolism Open, researchers found that fasting from dawn to dusk for four...

Tiny, implantable therapeutic sponge device helps kill cancer in mice
Post

Tiny, implantable therapeutic sponge device helps kill cancer in mice

by Wayne Lewis, University of California, Los Angeles The SymphNode device (left), contains nanoparticles (red dots) that release a drug that blocks the activity of regulatory T cells (green), which suppress the body’s response to solid tumors. At the same time, the SymphNode’s microparticles (black dots) attract and beef up cancer-fighting T cells. Credit: Negin...

The molecules behind metastasis
Post

The molecules behind metastasis

by Greta Friar, Whitehead Institute for Biomedical Research Breast cancer stem cells (red) that have reached the lung begin to divide into clusters that could become metastatic tumors. Credit: Arthur Lambert Many cancer cells never leave their original tumors. Some cancer cells evolve the ability to migrate to other tissues, but once there cannot manage...

Biochemists describe structure and function of newly discovered CRISPR immune system
Post

Biochemists describe structure and function of newly discovered CRISPR immune system

by Mary-Ann Muffoletto, Utah State University Credit: Utah State University Utah State University biochemists Thomson Hallmark and Ryan Jackson, along with collaborators, published two seminal papers this week. Their findings describe the structure and function of a newly discovered CRISPR immune system that—unlike better-known CRISPR systems that deactivate foreign genes to protect cells—shuts down infected cells...

A tool to investigate rare, previously inaccessible cells that play a key role in multiple sclerosis
Post

A tool to investigate rare, previously inaccessible cells that play a key role in multiple sclerosis

by Brigham and Women’s Hospital This is an astrocyte, labeled with GFAP (red), Focal Adhesion Kinase (FAK) green, and nuclear stain To-Pro (blue). Credit: Nathan S. Ivey at TNPRC. Via Wikipedia. Rare cell types can have an undue influence on human health. Previous research has suggested that a subset of astrocytes—star-shaped cells in the brain and spinal...

Gut bacteria may play a role in diabetes
Post

Gut bacteria may play a role in diabetes

by Cedars-Sinai Medical Center Correlations among abundance levels of 12 species associated with insulin homeostasis traits or dysglycemia. Correlation coefficients are displayed, with shades of red representing positive values and shades of blue representing negative values. The two clusters of species are outlined with squares. *P < 0.05 and >0.01; **P < 0.01 and ≥0.0001;...

Researchers reveal an added layer of nuance in our sense of smell
Post

Researchers reveal an added layer of nuance in our sense of smell

by Harrison Tasoff, University of California – Santa Barbara Under the previous model (top), an odor would activate an increasing number of olfactory sensory neurons as it’s concentration rose. The new findings (bottom) showed that the activity of the most sensitive neurons fell off as others joined. Credit: TADRES ET AL. The delicate fragrance of...

Researchers uncover how embryonic cells sense their mechanical environment to collectively form tissues
Post

Researchers uncover how embryonic cells sense their mechanical environment to collectively form tissues

UNIVERSITY OF CALIFORNIA – SANTA BARBARA IMAGE: ZEBRAFISH EMBRYO CREDIT: UC SANTA BARBARA Building tissues and organs is one of the most complex and important tasks that cells must accomplish during embryogenesis. Individual cells do not make these decisions; rather, building tissue is a collective task that requires cells to constantly communicate with each other....