SOCIETY OF NUCLEAR MEDICINE AND MOLECULAR IMAGING IMAGE: THIS FIGURE HIGHLIGHTS 3 PATIENTS WITH A FINAL DIAGNOSIS OF LOW-GRADE UPTAKE (PERUGINI GRADE-1). ENDOMYOCARDIAL BIOPSY RESULTS WERE AVAILABLE FOR THE PATIENT DEPICTED IN PANEL B DEMONSTRATING ATTR-CA AS THE UNDERLYING PATHOLOGY. CREDIT: IMAGE CREATED BY DEPARTMENT OF NUCLEAR MEDICINE, MEDICAL UNIVERSITY OF VIENNA, AUSTRIA. Reston, VA—A...
BOSTON CHILDREN’S HOSPITAL Neurofibromatosis type 1 (NF1) is a common genetic condition, affecting 1 in 3000 individuals, and people with NF1 are at greater risk of developing a rare, aggressive form of cancer. Diagnosing malignant peripheral nerve sheath tumors (MPNSTs) often comes too late, after the cancer has spread and is difficult to treat. But...
SALK INSTITUTE IMAGE: TIME-RESTRICTED EATING RESHAPES GENE EXPRESSION THROUGHOUT THE BODY. IN THIS ILLUSTRATION, THE FERRIS WHEEL DISPLAYS THE INTERCONNECTED ORGAN SYSTEMS WORKING SMOOTHLY DURING TIME-RESTRICTED EATING, WHICH IS REPRESENTED BY THE CLOCK IN THE MIDDLE. CREDIT: SALK INSTITUTE LA JOLLA (January 3, 2023)— Numerous studies have shown health benefits of time-restricted eating including increase...
by Massachusetts Institute of Technology A figure from the paper depicts pathways perturbed in Alzheimer’s disease. Examples are listed for each pathway by major brain cell type. Credit: Tsai Lab/MIT Picower Institute After decades of fundamental scientific and drug discovery research, Alzheimer’s disease has remained inscrutable and incurable, with a bare minimum of therapeutic progress. But...
by Salk Institute Graphical abstract. Credit: Cell Metabolism (2023). DOI: 10.1016/j.cmet.2022.12.004 Obesity and metabolic diseases, such as diabetes, are extremely common in the United States. Tiny proteins called microproteins have long been overlooked in research, but new evidence demonstrates that they have an important role in metabolism. Salk scientists have discovered that both brown and white fat is...
by Tracey Peake, North Carolina State University Linoleic acid (LA) metabolites are found in both the free and total pools of fatty acids in human skin. A box represents the schematic depiction of a) LA or oxylipins (i.e., 9,13-EHL and 9,10,13-THL) derived from LA are esterified into lipid membranes. b) Hydrolysis by enzymes such as...
by University of Manchester A) Published reports of histoplasmosis by state of residence of patients. B) Published reports of histoplasmosis according the authors’ institution, by state. Credit: Open Forum Infectious Diseases (2022). DOI: 10.1093/ofid/ofac603 Researchers from India and Manchester have shown that over fifty million Indians are affected by serious fungal disease, 10% of which are from potentially...
by Baylor College of Medicine Credit: CC0 Public Domain For chronic conditions such as rheumatoid arthritis, treatment often involves lifelong injections. Fear of needles, injection-associated infection and pain are responsible for patients skipping doses, which encourages the development of new delivery strategies that combine efficacy with limited side effects to treat patients adequately. Researchers at Baylor...
by Jim Schnabel, Cornell University Credit: Unsplash/CC0 Public Domain The post-COVID syndrome known as long COVID has four major subtypes defined by different clusters of symptoms, according to a study led by researchers at Weill Cornell Medicine. The study, published Dec. 1 in Nature Medicine, was the largest of its kind to examine long COVID. The researchers, who represent...
by Hong Kong Baptist University The research team of Professor Bian Zhaoxiang, Director of the Clinical Division and Tsang Shiu Tim Endowed Professor in Chinese Medicine Clinical Studies (middle); Dr Xavier Wong Hoi-leong, Assistant Professor of the Teaching and Research Division (right); and Dr Zhai Lixiang, Post-Doctoral Research Fellow (left) of SCM at HKBU, has shown for the first time that...
