by University of Copenhagen Enterotypes differ in stool energy density, intestinal transit time, microbial alpha-diversity, and body weight. a The study included baseline measurements of 85 overweight subjects. Prior to collection of the stool and urine samples used in the study, habitual dietary intake was estimated based on 4-day dietary registrations and intestinal transit time was estimated...
Wafer-thin device has potential to transform the field of islet cell transplantation
by Houston Methodist The Neovascularized Implantable Cell Homing and Encapsulation (NICHE) device is about the size of a quarter. Credit: Houston Methodist A quarter-sized device created at Houston Methodist could drastically alter the course of treatment for type 1 diabetes, a chronic condition that impacts millions of Americans and does not have a cure. In...
Eye tracking during visual challenges reveals neural encoding
by Weizmann Institute of Science Credit: Weizmann Institute of Science “Seeing eye to eye” is an expression of harmony, but do different people literally see the same thing when they view the same external world? “The short answer is—no,” says Dr. Liron Gruber. “Even the same person sees the same thing differently each time they...
Immunologists uncover obesity-linked trigger to severe form of liver disease
by UT Southwestern Medical Center Graphical abstract. Credit: Immunity (2022). DOI: 10.1016/j.immuni.2022.11.013 UT Southwestern immunologists have uncovered a key pathogenic event prompted by obesity that can trigger severe forms of nonalcoholic fatty liver disease and potential liver failure. The finding, published in Immunity, could pave the way for developing therapies to treat nonalcoholic steatohepatitis (NASH). The team led...
Risk for persistent postural perceptual dizziness increases with vestibular conditions, study finds
by Elana Gotkine HealthDay Reporter Patients with multiple vestibular conditions have an increased risk for persistent postural perceptual dizziness (PPPD), according to study published online Oct. 27 in Audiology Research. Valeria Gambacorta, M.D., from the University of Perugia in Italy, and colleagues analyzed the role of benign paroxysmal positional vertigo (BPPV), vestibular migraine (VM), and Ménière disease...
Brain area necessary for fluid intelligence identified
by University College London Credit: Pixabay/CC0 Public Domain A team led by UCL and UCLH researchers have mapped the parts of the brain that support our ability to solve problems without prior experience—otherwise known as fluid intelligence. Fluid intelligence is arguably the defining feature of human cognition. It predicts educational and professional success, social mobility, health, and...
New biomarker test can detect Alzheimer’s neurodegeneration in blood
by University of Pittsburgh Credit: Pixabay/CC0 Public Domain A group of neuroscientists led by a University of Pittsburgh School of Medicine researcher developed a test to detect a novel marker of Alzheimer’s disease neurodegeneration in a blood sample. A study on their results was published today in Brain. The biomarker, called brain-derived tau, or BD-tau, outperforms...
New technique improves high-intensity focused ultrasound treatment for brain disorders
by UT Southwestern Medical Center Graphical abstract. Credit: Brain Communications (2022). DOI: 10.1093/braincomms/fcac273 UT Southwestern physicians have developed an improved targeting method, four-tract tractography, to personalize MRI-guided, high-intensity focused ultrasound (HIFU) used at UTSW to treat medication refractory tremor in essential tremor and tremor-dominant Parkinson’s disease. Results of the clinical cases utilizing this approach, published in Brain Communications,...
Product of Gut Microbiome Implicated in Heart Failure Risk
Sue Hughes December 22, 2022 Further evidence that the gut microbiome affects the development of cardiovascular disease, heart failure in particular, has emerged in a new report. The study directly linked elevated levels of phenylacetylglutamine (PAG), a byproduct created when microbes in the gut break down dietary protein, to increased heart failure risk and severity. It follows previous studies...
Microbial Fuel Cell Powers Ingestible Devices
DECEMBER 27TH, 2022 CONN HASTINGS GI Researchers at Binghamton University have developed a microbial fuel cell that can power ingestible devices, such as cameras, that can detect health issues in the gastrointestinal tract, and specifically within the small intestine. The fuel cell contains dormant Bacillus subtilis endospores that only germinate and become active when they encounter nutrient-rich intestinal fluid....