Month: <span>January 2023</span>

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Targeting tau, the other protein behind Alzheimer’s disease
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Targeting tau, the other protein behind Alzheimer’s disease

by Leila Gray, University of Washington School of Medicine Defective tau proteins form insoluble neurofibrillary tangles (green) that cause neurons to die. Credit: Kraemer Lab In November, researchers reported the drug lecanemab slowed the progression of Alzheimer’s disease. The effect was modest, but it has generated tremendous excitement because it was the first time a drug had...

Investigators develop new therapy for autism subtype
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Investigators develop new therapy for autism subtype

by Melissa Rohman, Northwestern University Credit: Pixabay/CC0 Public Domain A team of Northwestern investigators led by Peter Penzes, Ph.D., the Ruth and Evelyn Dunbar Professor of Psychiatry and Behavioral Sciences and director of the Center for Autism and Neurodevelopment, has developed a new therapy that could treat Phelan-McDermid syndrome, a subtype of autism spectrum disorder...

Making pig livers humanlike in quest to ease organ shortage
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Making pig livers humanlike in quest to ease organ shortage

by Lauran Neergaard  A pig kidney that has been “decelled” is held by a technician in a Micromatrix laboratory on Tuesday, Dec. 8, 2022, in Eden Prairie, Minn. This is a pig kidney that’s gradually being transformed to look and act like a human one, part of scientists’ long quest to ease the nation’s transplant...

Xanthan gum-based fluid thickener can help decrease blood glucose levels
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Xanthan gum-based fluid thickener can help decrease blood glucose levels

TOKYO MEDICAL AND DENTAL UNIVERSITY IMAGE: FIG.1: LONG-TERM CONSUMPTION OF THE XANTHAN GUM-BASED FLUID THICKENER. CREDIT: DEPARTMENT OF DYSPHAGIA REHABILITATION, TMDU Researchers from Tokyo Medical and Dental University (TMDU) showed that xanthan gum-based fluid thickener can decrease blood glucose levels after eating Tokyo, Japan -Type 2 diabetes mellitus is a common lifestyle disease that is prevalent worldwide....

New method predicts the right treatment for breast cancer patients
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New method predicts the right treatment for breast cancer patients

by Karolinska Institutet The researchers developed and tested whole-tumor cell culture models derived from breast cancer patients that can predict how the tumors will respond to different treatments. Credit: Xinsong Chen et al, PNAS 2022 Researchers at Karolinska Institutet have developed a method that should be able to predict whether a patient with breast cancer will benefit from a particular...

Researchers study pain-relieving neural mechanisms by activation of the motor cortex
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Researchers study pain-relieving neural mechanisms by activation of the motor cortex

by Universitätsklinikum Heidelberg  Stained nerve tracts in the motor cortex of a mouse. Credit: Heidelberg University Hospital The motor cortex controls the voluntary movement of muscles. It remains largely unclear why its electrical or magnetic stimulation can alleviate therapy-resistant chronic pain—albeit unreliably. An interdisciplinary research group at the Medical Faculty of Heidelberg (MFHD) has now tracked down...

New blood test to identify infections could reduce global antibiotic overuse
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New blood test to identify infections could reduce global antibiotic overuse

by Nina Bai, Stanford University Medical Center Tuberculosis bacteria replicate inside human cells, as viruses do. A blood test developed at Stanford Medicine can distinguish between such bacteria and viruses with 90% accuracy. Credit: Kateryna Kon/Shutterstock In developing countries, most antibiotic prescriptions are not only pointless—an estimated 70% to 80% of them are given for...

When the body’s B cell training grounds stay open after hours
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When the body’s B cell training grounds stay open after hours

by Rockefeller University Graphical abstract. Credit: Cell (2022). DOI: 10.1016/j.cell.2022.11.031 If B cells are the munitions factories of the immune system, manufacturing antibodies to neutralize harmful pathogens, then the tiny biological structures known as germinal centers are its weapons-development facilities. Formed in response to infection and vaccination, these microscopic training grounds allow B cells to perfect the...

Females on average perform better than males on a ‘theory of mind’ test across 57 countries
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Females on average perform better than males on a ‘theory of mind’ test across 57 countries

by University of Cambridge Credit: Pixabay/CC0 Public Domain Females, on average, are better than males at putting themselves in others’ shoes and imagining what the other person is thinking or feeling, suggests a new study of over 300,000 people in 57 countries. Researchers found that females, on average, score higher than males on the widely used...

AI-powered technology sees big improvements in UK stroke treatment: analysis
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AI-powered technology sees big improvements in UK stroke treatment: analysis

Micrograph showing cortical pseudolaminar necrosis, a finding seen in strokes on medical imaging and at autopsy. H&E-LFB stain. Credit: Nephron/Wikipedia Artificial intelligence technology has tripled the number of UK stroke patients recovering to a point where they can perform daily activities, according to new research released on Tuesday. Early stage analysis of over 111,000 suspected stroke patients whose care...