by Marie-Morgane Le Moel with Daniel Lawler in Paris The cells of an “artificial skin” being developed by French company Urgo. Far from the humble sticking plaster, medical firms and researchers are seeking to create the “ultimate dressing”—artificial skin they hope will revolutionize the treatment of severe burns. For the last 18 months, researchers from the French firm Urgo...
Researchers map activity of inherited gene variants linked to prostate cancer
by UT Southwestern Medical Center Credit: Pixabay/CC0 Public Domain UT Southwestern researchers have identified the molecular function of 87 inherited genetic variants that affect the risk of prostate cancer, and the majority appear to control the activity of genes located far away from the risk variants themselves. The findings, published in Cancer Discovery, could lead to better ways...
Calorie restriction trial reveals gene that may prolong healthy life
A new study investigates calorie restriction in humans. Catherine MacBride/Stocksy Laboratory studies have found that some animals on calorie-restricted diets live longer. Researchers are keen to find out whether there is a similar effect in people. Now, a small-scale study suggests that moderate calorie restriction may benefit human health. The researchers identified a key protein that might increase...
Magnesium may prime the immune system to fight cancer and infections
Walnuts are a rich source of magnesium. simonkr/Getty Images Magnesium deficiency has links to a wide range of diseases. Researchers have now shown in mice how magnesium improves the ability of the immune system to eliminate infected and cancerous cells. Their analysis of data from clinical studies also suggests that low serum levels of the substance...
Long COVID: Could mono virus or fat cells be playing roles?
by Lindsey Tanner This photo provided by Amy Watson of Portland, Ore., shows her during an iron infusion in December 2022. Watson, approaching 50, says she has “never had any kind of recovery” from COVID-19. She has had severe migraines, plus digestive, nerve and foot problems. Recently she developed severe anemia. Credit: Amy Watson via...
A protective probiotic for ALS found
by Bruno Geoffroy, University of Montreal Hospital Research Centre Neuroprotection mechanism of Lacticaseibacillus rhamnosus HA-114. ALS models have impaired carnitine shuttle, a mechanism to transport long chain fatty acids across the mitochondrial membrane for energy production via β-oxidation. Fatty acids, supplied by the probiotic bacteria, is believed to enter the mitochondria independently of the carnitine...
Treating gut pain via a Nobel prize-winning receptor
by Flinders University Credit: Pixabay/CC0 Public Domain Targeting a receptor responsible for our sense of touch and temperature, which researchers have now found to be present in our colon, could provide a new avenue for treating chronic pain associated with gastrointestinal disorders such as irritable bowel syndrome. A team examining the colon, led by Professor Hongzhen Hu...
New bacterial therapy approach to treat lung cancer
by Holly Evarts, Columbia University School of Engineering and Applied Science Fluorescence microscopy image of lung cancer cells stained with antibodies against proteins involved in cellular growth. Credit: Dhruba Deb/Columbia Engineering Lung cancer is the deadliest cancer in the United States and around the world. Many of the currently available therapies have been ineffective, leaving...
Male and female stem cells created from single person for the first time
By Michael Irving December 22, 2022 Scientists have created stem cells that are genetically identical except for their sex chromosomes, paving the way for a powerful platform for studying sex differences in biology and medicineDepositphotos Scientists in Israel have for the first time created male and female stem cells from the same person. This breakthrough...
Lab results alone don’t give full picture of antiphospholipid syndrome
by Valerie Goodwin, University of Michigan Associations between patient-reported outcomes for physical function, cognitive function, and pain intensity (n = 130 for A and C; n = 139 for B). Pearson r and associated P values are indicated. aPL, antiphospholipid antibodies; APS, antiphospholipid syndrome. Credit: ACR Open Rheumatology (2022). DOI: 10.1002/acr2.11512 Antiphospholipid syndrome is an autoimmune disease that preferentially affects women. Patients with APS are...