VAN ANDEL RESEARCH INSTITUTE IMAGE: DR. CONNIE KRAWCZYK CREDIT: COURTESY OF VAN ANDEL INSTITUTE. GRAND RAPIDS, Mich. (April 19, 2023) — Van Andel Institute scientists have pinpointed a key driver of low bone density, a discovery that may lead to improved treatments with fewer side effects for women with osteoporosis. The findings are described in a study published this month in Science...
NYU LANGONE HEALTH / NYU GROSSMAN SCHOOL OF MEDICINE IMAGE: HAIR-COLORING STEM CELLS (AT LEFT, IN PINK) NEED TO BE IN THE HAIR GERM COMPARTMENT IN ORDER TO BE ACTIVATED (AT RIGHT) TO DEVELOP INTO PIGMENT. CREDIT: COURTESY OF SPRINGER-NATURE PUBLISHING OR THE JOURNAL NATURE Certain stem cells have a unique ability to move between...
by Wiley Credit: Pixabay/CC0 Public Domain In research published in The FASEB Journal, scientists have discovered that a molecule called Yes-associated protein (YAP) plays a key role in the development of liver scarring, or fibrosis, by influencing the behavior of premature cells called liver progenitor cells. By manipulating YAP expression in these cells, the investigators were able to improve...
by Justin Jackson, Medical Xpress Graphic summary of the study design. In this study, we evaluate four hypotheses: (i) Age-parsed networks in neurotypical brains explain more SCZ genetic risk than the same data not age-parsed. (ii) The course of SCZ enrichment differs between NCs and patients with SCZ. (iii) There is a molecular environment to...
by Niigata University Credit: Pixabay/CC0 Public Domain Researchers from Niigata University and Kyoto Prefectural University have revealed that small vesicles, around 100 nm in size, released by intestinal bacteria induce immune activation and progression of liver cirrhosis, as well as a reduction of serum albumin levels, subsequently leading to edema and ascites. The research is published in the...
by Stephanie McPherson, Broad Institute of MIT and Harvard Human pancreatic beta cells show increased membrane rigidity (indicated in red) when exposed to erucic acid, a toxic monounsaturated fatty acid. Credit: Ranjan Devkota and Juliana Coraor Fried Researchers have developed a technology, FALCON, to analyze the effects of free fatty acids in any cell type, and found...
by Houston Methodist Model-predicted optimal dosing and CDC-recommended dosing schedules for the Pfizer-BioNTech vaccine in healthy and immunocompromised sub-populations. The ongoing CDC guidelines for dosing schedules are represented by the blue bands and those predicted by the model are shown in green. Credit: (2022). DOI: 10.1101/2022.09.14.22279959 With the FDA authorizing a second bivalent booster this week for...
by University of Turku Principal Component Analysis of the serum metabolic profiles of the study participants in early (n = 174) and late pregnancy (n = 159) and prediabetes status at two years postpartum. Blue = no prediabetes and red = prediabetes. Credit: Metabolomics (2023). DOI: 10.1007/s11306-023-01994-z Researchers from the University of Turku in Finland discovered that women who developed prediabetes after pregnancy had aberrations already in...
by Newcastle University Professor Roy Taylor, Newcastle University. Credit: Newcastle University New findings have revealed that nearly a quarter (23%) of participants who were in remission from type 2 diabetes at two years in a clinical trial remained in remission at five years. The participants no longer needed to use diabetes medications to manage their blood sugar levels. Those...
BRIGHAM AND WOMEN’S HOSPITALP Brand-name drugs cost two to three times more in the U.S. than in other countries, but many of the top-selling brand name drugs may provide little added therapeutic benefit. A new study led by researchers at Brigham and Women’s Hospital, a founding member of Mass General Brigham, used public Medicare data to identify the 50...
