Month: <span>April 2023</span>

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Association of alleles with risk of relapse in ANCA-associated vasculitis in the Japanese population

by University of Tsukuba Credit: luchschenF/Shutterstock Vasculitis is a group of conditions that results in inflammation of the blood vessels. Symptoms include rash, shortness of breath, vision loss, and kidney failure depending on the location of the inflamed vessels. A rare type of vasculitis, ANCA-associated vasculitis (AAV), is associated with the presence of antineutrophil cytoplasmic...

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Two cancer research studies reveal essential role of neutrophils in immunotherapy

by  Ludwig Institute for Cancer Research Graphical abstract. Credit: Daniel Hirschhorn et al, T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants, Cell (2023). DOI: 10.1016/j.cell.2023.03.007 Two independent Ludwig Cancer Research studies published in the current issue of the journal Cell show that immune cells known as neutrophils, whose abundance in the microenvironment of tumors has traditionally...

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New approach to slowing aggressive leukemia

by Yahya Chaudhry,  Harvard University Graphical abstract. Credit: Cancer Cell (2023).DOI:10.1016/j.ccell.2023.02.010. A team of Harvard and Sloan Kettering scientists has developed compounds that can target and degrade proteins associated with acute myeloid leukemia (AML) and nearly doubled the life expectancy of mice with cancer in laboratory tests. Because the degradation of these proteins blocks cell growth and delays...

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Non-drug interventions for patients with Alzheimer’s are both effective and cost-effective, study shows

by  Brown University Credit: Pixabay/CC0 Public Domain While new drugs to treat Alzheimer’s disease tend to receive the most public attention, many well-researched ways to care for people with dementia don’t involve medication. A new evaluation compared the cost-effectiveness of four non-drug interventions to the usual care received by people with dementia and found that the...

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Fasting diet reduces risk markers of type 2 diabetes, study finds

by University of Adelaide Weight loss (kg) relative to baseline. Presented are means and 95% CIs of the non-fasting weight change by group during each face to face check-in visit. Treatment group trajectories were compared using linear mixed effects regression assuming piecewise linear effects assumed for the interventions over two time periods: month 0–6 and...

What does the mouth do in the digestive system?
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What does the mouth do in the digestive system?

The mouth starts the digestion process by breaking food down into a more easily digestible form. Pinterest Melissa Milis Photography/Getty Images After people take food in through the mouth, it moves down the throat, also known as the pharynx. It then passes through the esophagus and into the stomach. Read on to learn more about...

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Chanca piedra: Does it treat gallstones?

Chanca piedra is a plant with a history of use in traditional medicine. There is some interest in using chanca piedra to break down kidney stones and gallstones, though scientific evidence is lacking on its effectiveness. Phyllanthus niruriis a perennial shrub that grows throughout tropical and subtropical regions. Chanca piedra is the Spanish name for P....

Doctors reveal the six surprising things that can trigger your migraines — including cheeses, certain perfumes and even SEX
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Doctors reveal the six surprising things that can trigger your migraines — including cheeses, certain perfumes and even SEX

Migraine is a disorder marked by hypersensitivity to light, sounds, doctors say  Some surprising triggers of migraine include relaxing, aged cheese, and anger Migraines can take days to clear and affect more than 39 million Americans   By CASSIDY MORRISON SENIOR HEALTH REPORTER FOR DAILYMAIL.COM UPDATED: 07:44 EDT, 2 April 2023 Migraines are more than just headaches, as any...

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To ice or not to ice? Icing can promote muscle regeneration after mild injury

by  Kobe University Fig. 1. Left: Method of inducing mild muscle injury. While under anesthetic, the protractor muscle in the animal’s hind leg is exposed and then clamped by forceps with a 250g weight attached. Right: The muscle injuries induced using this method affect around 4% of total myofibers. C Shows that this method enables mild...