by Melissa Rohman, Northwestern University Chronic corticosterone treatment significantly decreases tissue dopamine content of the dorsomedial striatum (DMS) in female mice. A Experimental timeline for pellet implantation, tissue punches, and HPLC-ECD of dopamine. B Tissue dopamine content of the nucleus accumbens core (NAcc) of placebo- and CORT-treated male and female mice. C Tissue dopamine content of...
Research follows earlier OHSU findings that chronic cannabis use inhibits male fertility in animal models; will help inform patient considerations of THC when trying to conceive OREGON HEALTH & SCIENCE UNIVERSITY A 2022 study from Oregon Health & Science University researchers confirmed that chronic use of cannabis may greatly impact male fertility and reproductive outcomes in nonhuman...
MARY ANN LIEBERT, INC./GENETIC ENGINEERING NEWS IMAGE: THE LATEST ADVANCES AT THE INTERSECTION OF POSTGENOMICS MEDICINE, BIOTECHNOLOGY AND GLOBAL SOCIETY, INCLUDING THE INTEGRATION OF MULTI-OMICS KNOWLEDGE, DATA ANALYSES AND MODELING, AND APPLICATIONS OF HIGH-THROUGHPUT APPROACHES TO STUDY COMPLEX BIOLOGICAL AND SOCIETAL PROBLEMS. PUBLIC POLICY, GOVERNANCE AND SOCIETAL ASPECTS OF THE LARGE-SCALE BIOLOGY AND 21ST CENTURY...
JOHNS HOPKINS MEDICINE The breast tumors of Asian, Black and white women have very different cellular, microbial and genomic features that could potentially be used to personalize care or predict disease progression, according to new research by investigators at the Johns Hopkins Kimmel Cancer Center. Potential race-specific microbial biomarkers of breast cancer identified by the researchers...
By Bronwyn Thompson March 26, 2023 A change in the brain’s neural pathways while dieting facilitates rebound weight gain Depositphotos Anyone who has achieved it knows that maintaining weight loss long-term is an uphill battle. The hormonal, metabolic and neural factors that regulate body weight means it can be more a matter of biology than willpower. At...
By Paul McClure March 26, 2023 Scientists have identified the role that an enzyme found in every single living cell plays in the development of kidney disease Depositphotos Scientists have identified the role an enzyme, crucial to the body’s metabolism, plays in the development of kidney disease, opening the door to new methods of prevention...
MARY ANN LIEBERT, INC./GENETIC ENGINEERING NEWS IMAGE: FOCUSES ON THE LATEST ADVANCES IN THE CLINICAL AND LABORATORY INVESTIGATION OF TRAUMATIC BRAIN AND SPINAL CORD INJURY. EMPHASIS IS ON THE BASIC PATHOBIOLOGY OF INJURY TO THE NERVOUS SYSTEM, AND THE PAPERS AND REVIEWS EVALUATE PRECLINICAL AND CLINICAL TRIALS TARGETED AT IMPROVING THE EARLY MANAGEMENT AND LONG-TERM...
Study suggests that light therapy may be effective at slowing cardiovascular aging Peer-Reviewed Publication UNIVERSITY AT BUFFALO BUFFALO, N.Y — Light therapy has demonstrated its usefulness in treating a variety of diseases. But can it delay the occurrence of age-related disease? The answer may be yes, according to a study in mice published in February...
By Dr. Liji Thomas, MD Mar 19 2023 Reviewed by Danielle Ellis, B.Sc. Parkinson’s disease (PD) is an incurable neurodegenerative disease that affects one in a hundred people the world over, second only to Alzheimer’s disease in the number of people affected. However, the mechanism by which it arises is still unclear. In a new research...
Ted Bosworth February 01, 2023 A Mendelian randomization study employing data from nearly 300,000 individuals has linked elevated levels of the PCSK9 enzyme with an increased risk of psoriasis, suggesting it might be targetable as an intervention. Independent of low-density lipoprotein cholesterol (LDL-C), which is reduced when PCSK9 is inhibited, a reduction in PCSK9 levels appears to have a direct...
