by Angela Nicoletti, Florida International University Credit: Florida International University Guilarte and Timothy Allen, director of the Neurocircuitry & Cognition Lab, are working together to investigate the effectiveness of the flavonoid 7,8-dihydroxyflavone in improving learning after lead exposure. Tomás R. Guilarte has been exchanging emails with a mother whose child was exposed to lead. She’s...
Bacteria-based cancer therapy reactivates vaccines you’ve already had
By Michael IrvingScientists have shown that it might be possible to fight cancer by reactivating vaccines you’ve already had DepositphotosVaccines against cancer are somewhat of a holy grail for medicine – but what if you could repurpose a vaccine you’ve already had? Scientists have demonstrated in mice a way to trick the immune system into...
Unlocking secrets of immune system proteins: A potential path to new treatments
Detailed imaging reveals intricate workings of key receptors, offering fresh insights into combating disease. Peer-Reviewed PublicationUNIVERSITY OF SOUTHERN CALIFORNIA Anaphylatoxin Recognition CREDIT: JAGANNATH MAHARANA/IIT KANPUR In the intricate dance of our body’s defenses against harmful invaders, certain immune system proteins play pivotal roles. New research from the Bridge Institute at the USC Michelson Center for...
Research offers new approach to nongenetic T-cell-based immunotherapy
by Wiley Credit: WileyImmunotherapies for cancer aim to induce the immune system to combat cancer cells more effectively. In the journal Angewandte Chemie International Edition, a Chinese research team has now described a new, modular strategy for T-cell-based immunotherapy that manages to work without complex genetic modifications. Modulation of cell–cell communications through an ingenious regulatory...
Toppling information silos to link electronic dental and health records
by Regenstrief Institute Other autoimmune conditions in the study cohort and by three Sjögren’s disease (SD) groups. Other autoimmune conditions such as rheumatoid arthritis, systemic lupus erythematous, inflammatory polyarthropathy represent more than 10% among SD patients. Total: study cohort; positive, uncertain, negative represent the three SD groups by clinical characteristics. Credit: PLOS ONE (2023). DOI:...
Scientists find evidence of unintended impacts from anti-cancer drugs
by Stowers Institute for Medical Research Fluorescent image showing cells with normal nucleoli (bright orange) in nuclei (purple) surrounded by actin filaments (dark blue). Credit: Tamara Potapova, Gerton Lab, Stowers Institute for Medical Research.With around 90% of drugs failing to make it to market, the potential for improving efficiency within the drug development industry is...
New research shows how cancer rewires a key immune pathway to spread
by Weill Cornell Medical College A collaboration between MSK and Weill Cornell Medicine used an approach called ContactTracing to predict the effect of interactions between cells in the tumor microenvironment. The segments of the outer ring represent cell types, and the colored lines highlight ligand-receptor-mediated interactions that depend on a tumor intrinsic process called chromosomal...
Sensory neurons develop customized nerve endings based on cues from the skin, study suggests
by Christy Brownlee, Harvard Medical School Graphical Abstract. Credit: Developmental Cell (2023). DOI: 10.1016/j.devcel.2023.07.020Nerve cells that sense touch grow the appropriate endings for hairy or hairless skin based on cues from the skin itself, rather than through predetermined programming, according to research led by Harvard Medical School scientists and published Aug. 21 in Developmental Cell....
What this CDC report reveal about long Covid in children?
ReutersA new report suggested that in 2022, 1% of children in the United States suffered from long-term Covid-19 symptoms, as researchers showed that those infected with the virus can sustain several signs for months. According to the report recently published by the Centers for Disease Control and Prevention, about 92% of those 17 and younger...
Why non-melanoma skin cancer is now more deadly than melanoma worldwide
Experts say you should have a dermatologist check your skin on a regular basis. Lord Henri Voton/Getty ImagesNon-melanoma skin cancers accounted for more deaths worldwide than melanoma because they are much more common.The growing aging population could be one reason skin cancer rates are increasing.Non-melanoma skin cancer is treatable and, in most cases, preventable.A study...