By Anika NayakOct. 11, 2023 APSTOCKChronic kidney disease was the strongest risk factor for sudden cardiac arrest among Hispanic and Latino adults in the first study to evaluate this population in the U.S. for risk factors of this major cause of death. Researchers from Cedars–Sinai Medical Center in Los Angeles identified clinical predictors that influence...
by Denise Heady, University of California, Los Angeles Drug screening identifies RAF and ERK as the mediators of IFNγ-induced growth inhibition. (A) Workflow for the drug screen. The orange dots on the Z-score plot indicate expected hits that rescue IFNγ-mediated growth inhibition but do not affect cell growth in the absence of IFNγ. (B) Z-score plot...
Heidi Splete October 06, 2023TOPLINE:Matched cohort studies revealed infrequent adverse events (AEs) with either treatment, but the number needed to harm for any AE was more than three times higher with colchicine vs NSAIDs. METHODOLOGY:The researchers conducted two matched retrospective cohort studies using the UK Clinical Practice Research Datalink and the Hospital Episode Statistics primary...
Ute Eppinger October 05, 2023 Thyroxine and L-thyroxine are two of the 10 most frequently prescribed medicinal products. “One large health insurance company ranks thyroid hormone at fourth place in the list of most-sold medications in the United States. It is possibly the second most commonly prescribed preparation,” said Joachim Feldkamp, MD, PhD, director of the University...
Arianna Sarjoo October 02, 2023 One in three patients who experience their first bout of atrial fibrillation (AF) during hospitalization can expect to experience a recurrence of the arrhythmia within the year, new research shows. The findings, reported today in the Annals of Internal Medicine , suggest these patients may be good candidates for oral anticoagulants to...
Miriam E. Tucker October 06, 2023 HAMBURG, Germany — The “twincretin” tirzepatide (Mounjaro) kept on producing “highly significant weight loss” when the drug was continued in a 1-year follow-up trial, and those who discontinued the drug regained some weight but not all. In Eli Lilly’s SURMOUNT-4 trial of 783 adults with obesity or overweight but not diabetes...
By Katie Palmer Oct. 10, 2023 ADOBEA growing number of AI tools are being used to predict everything from sepsis to strokes, with the hope of accelerating the delivery of life-saving care. But over time, new research suggests, these predictive models can become a victim of their own success — sending their performance into a...
by Zhang Nannan, Chinese Academy of Sciences Credit: Pixabay/CC0 Public DomainVirtual reality (VR) can be used to modify patients’ experience of pain. However, the current understanding of what type of VR content is the best for pain relief and the neurobiological mechanisms underlying VR analgesia remain unclear. To address this, a team of researchers from the...
By Paul McClureOctober 15, 2023 DepositphotosA study has found that moderate calorie restriction can bolster the expression of healthy aging genesA study has found that moderate calorie restriction can bolster the expression of healthy aging genesA new study has investigated the biological mechanisms brought about by calorie restriction and found that a moderate reduction in...
by University of Michigan Credit: CC0 Public DomainMost people think of dementia as something that affects a person’s brain. But a new study shows just how much damage it does to a person’s wallet and bank account too—as well as the higher demands it places on their family members. In all, people diagnosed with dementia saw...
