by Flinders University Anterogradely labeled vagal afferent axons in the mid colon. a Single fine vagal axons course over the mucosa surface, with no preferential direction that aligns with the underlying crypts. Two different types of ending are shown in a, a complex- and simple-type ending. b An enlarged image from panel a. The complex ending...
Vision impairment linked to several psychosocial outcomes in seniors
by Elana Gotkine In adults 65 years and older, vision impairment is associated with psychosocial outcomes, including symptoms of depression, anxiety, and social isolation, according to a study published online Feb. 22 in JAMA Ophthalmology. Louay Almidani, M.D., from the Johns Hopkins University School of Medicine in Baltimore, and colleagues conducted a cross-sectional analysis of...
Predicting immunotherapy success via biomarkers
by Technion – Israel Institute of Technology Graphical abstract. Credit: Cancer Cell (2024). DOI: 10.1016/j.ccell.2023.12.005Researchers at the Technion’s Ruth and Bruce Rappaport Faculty of Medicine and the Rappaport Family Institute for Research in the Medical Sciences have discovered a subset of blood cells that predict the success of immunotherapy treatment. These findings are expected to streamline...
Overcoming dental fear with the tap of an app
by Rachel Harrison, New York University Dental FearLess app. Credit: David Song/NYUDoes the idea of sitting in a dental chair make your palms sweat? Or do you simply avoid making appointments altogether? You’re not alone. Research shows that 30% of people fear going to the dentist, including more than 20% who have had an appointment recently,...
Simple measurement can predict risk of worsening of widespread kidney disease
by Aarhus University Graphical Abstract. Credit: Nephrology Dialysis Transplantation (2024). DOI: 10.1093/ndt/gfad271About ten percent of the Danish population suffers from chronic kidney disease, and some individuals experience rapid deterioration after the diagnosis is made. Now, a team of researchers from Aarhus University in a comprehensive study has investigated the precise risk of rapid progression, and the...
Elusive immune cells dwelling in ‘hidden niches’ of the bone marrow may be key to SARS-CoV-2 vaccination
by Delthia Ricks , Medical Xpress Credit: CC0 Public DomainAlthough immunologists have developed a deep reservoir of knowledge illuminating how antibodies respond to vaccination against SARS-CoV-2, little is known about the elusive cells that produce infection-fighting antibodies. Although antibodies are among the first responders when infectious agents invade the body, they’re produced by mystifying cells...
Drug-resistant tuberculosis responds rapidly to bedaquiline-based second-line therapy
Peer-Reviewed Publication WEILL CORNELL MEDICINE IMAGE OF MYCOBACTERIUM TUBERCULOSISCREDIT: UNITED STATES CENTERS FOR DISEASE CONTROL AND PREVENTION Patients who have drug-resistant tuberculosis (TB) have a similar microbiological response to bedaquiline-based second-line medications as patients with drug-sensitive TB taking first-line regimens, according to researchers at Weill Cornell Medicine in New York and GHESKIO Centers in Haiti....
New clinical practice guideline provides evidence-based recommendations for immunotherapy for inhalant allergy
by American Academy of Otolaryngology — Head and Neck Surgery Credit: CC0 Public DomainThe American Academy of Otolaryngology–Head and Neck Surgery Foundation has published the Clinical Practice Guideline: Immunotherapy for Inhalant Allergy in Otolaryngology–Head and Neck Surgery. This clinical practice guideline identifies quality improvement opportunities and provides clinicians trustworthy, evidence-based recommendations on the management of...
Abdominal fat depots can impact brain health and cognition in individuals at high risk for Alzheimer’s disease
by Rutgers University Credit: Pixabay/CC0 Public DomainThe impact of abdominal fat on brain health and cognition is generally more pronounced in middle-aged men at high risk of Alzheimer’s disease than in women, according to researchers at Rutgers Health. In middle-aged individuals with a family history of Alzheimer’s disease, the amount of fat in their abdominal organs...
Scientists devise novel strategy to seek and destroy leukemia stem cells
by City of Hope National Medical Center Type II interferon (IFNy), a substance produced by immune cells, disrupts the leukemia stem cells’ ability to divide and spread cancer. However, IFNy also stimulates CD38, a protein that suppresses the immune cells’ ability to mount a response against infection. To overcome this challenge, City of Hope researchers designed...