Original story from the George Institute for Global HealthA 3D model of a human brain.Credit: Robina Weermeijer / Unsplash. A new analysis involving over 13,000 people has found changes to blood vessels in the brain that can increase the risk of stroke and dementia are common in people with a range of heart conditions, regardless...
Junk Proteins” Associated With Cause of Aging and ALS Progression
Original story from CNIOAccumulation of “junk proteins”: normal cells (left) and cells subjected to the effect of the toxic arginine-rich protein (right). In the latter, ribosomal proteins (green fluorescent) and the size of nucleoli (red) are increased.Credit: CNIO. Amyotrophic lateral sclerosis (ALS) is a degenerative disease. The neurons responsible for movement begin to die and...
New understanding of the gut immune system may hold promise for Crohn’s disease patients
A team of scientists from DTU and other European universities have uncovered an overlooked mechanism in the gut immune system of patients suffering from severe cases of Crohn’s disease. The discovery may help define how to treat patients with severe Crohn Peer-Reviewed PublicationTECHNICAL UNIVERSITY OF DENMARK Tricks played by certain disease-driving gut bacteria might help...
Advancing toward wearable stretchable electronics
STANFORD UNIVERSITY RESEARCHERS FROM THE STANFORD CENTER FOR AEROSPACE AUTONOMY RESEARCH (CAESAR) IN THE ROBOTIC TESTBED, WHICH CAN SIMULATE THE MOVEMENTS OF AUTONOMOUS SPACECRAFT. view moreCREDIT: ANDREW BRODHEAD Small wearable or implantable electronics could help monitor our health, diagnose diseases, and provide opportunities for improved, autonomous treatments. But to do this without aggravating or damaging...
Understanding chronic liver disease through mitochondria
by First Hospital of Jilin University (1) Degradation of mitochondria matrix, inner membrane and intermembrane oxidized or misfolded protein by mitochondrial proteases. (2) Ubiquitinated outer mitochondrial membrane proteins are extracted and degraded by the ubiquitin-proteasome system. (3) A portion of mitochondria budding off as mitochondria-derived vesicles and fuse with lysosomes for degradation. (4) Depolarized mitochondria...
Steroid drugs used for HRT can combat E. coli and MRSA
UNIVERSITY OF KENT The emergence of drug-resistant bacteria is a global threat to human health, and the development of new antibiotics from scratch is an extremely expensive and time-consuming process. To address this urgent issue, researchers from the University of Kent’s School of Biosciences have combined computational and microbiology laboratory approaches to identify existing drugs...
The integrity of the blood-brain barrier depends on a protein that is altered in some neurodegenerative diseases
Vascular defects and neuroinflammationUNIVERSITY OF BARCELONA IMAGE: FROM LEFT TO RIGHT, THE EXPERTS PILAR VILLACAMPA, VÍCTOR ARRIBAS AND ELOI MONTAÑEZ, FROM THE FACULTY OF MEDICINE AND HEALTH SCIENCES OF THE UNIVERSITY OF BARCELONA AND IDIBELL. view moreCREDIT: UNIVERSITY OF BARCELONA Defects in the blood vessel network of the central nervous system have been linked to...
New findings on the prevention of heart attacks and strokes
Novel approach for the treatment of vascular deposits identified MEDICAL UNIVERSITY OF VIENNA Blockage of arterial blood vessels caused by atherosclerosis is largely responsible for heart attacks and strokes, which are the most common causes of death worldwide. The complex mechanisms that lead to pathological changes in the arteries are not yet fully understood. An...
HKU scientists unveil significant discovery with potential impact on obesity and osteoporosis treatments
THE UNIVERSITY OF HONG KONG SECRETIN SIGNALING IN THE VENTROMEDIAL HYPOTHALAMUS REGULATES SKELETAL AND METABOLIC HOMEOSTASIS. IMAGE ADAPTED FROM RESPECTIVE PAPER IN NATURE COMMUNICATIONS (2024) view moreCREDIT: THE UNIVERSITY OF HONG KONG A team of researchers from The University of Hong Kong (HKU) has made a significant breakthrough in understanding how energy metabolism and bone...
Hope for treating sleep disorders, no pills required
FLINDERS UNIVERSITY IMAGE: DR ALEXANDER SWEETMAN, FLINDERS UNIVERSITY view moreCREDIT: FLINDERS UNIVERSITY Are sleeping pills the only solution for insomnia? Not according to Flinders University’s Dr Alexander Sweetman, who says that using self-guided digital behavioural therapy is an alternative solution that should be considered. Despite a wealth of evidence supporting the effectiveness of cognitive behavioural...