October 1, 2024 by Misti Crane, The Ohio State University Box plots of energy-adjusted dietary inflammatory index scores by two-year National Health and Nutrition Examination Survey cycles. The range of observed E-DII scores was -5·96 (anti-inflammatory dietary potential) to 4·90 (pro-inflammatory dietary potential). (Bars represent the interquartile range; dots represent outliers.) E-DII, energy-adjusted dietary inflammatory...
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Vitamin deficiencies common in children with nocturnal enuresis
October 1, 2024 by Lori Solomon Children with primary nocturnal enuresis may have vitamin D insufficiency and deficiency as well as vitamin B12 deficiency, according to a study published online June 10 in Annals of Medicine. Hoda Atef Abdelsattar Ibrahim, from Cairo University, and colleagues examined the prevalence of vitamin D and vitamin B12 deficiencies...
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Weight-adjusted waist index positively tied to overactive bladder
October 1, 2024 by Lori Solomon The weight-adjusted waist index (WWI) may be able to predict future incidence of overactive bladder (OAB) in adults, according to a study published online Sept. 3 in Frontiers in Nutrition. Zeng Hui, from the Third Xiangya Hospital at Central South University in Changsha, China, and colleagues used data from...
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Is gene therapy the next big step in vision loss treatment?
Diseases that affect the retina, the light-sensitive layer at the back of the eye, are a significant cause of visual impairment and blindness. Gene therapy holds promise for treating some of these conditions, and current research advances may soon shift the therapeutic landscape for eye health. However, many obstacles remain in place, as this Special...
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New biomaterial regrows damaged cartilage in joints
Northwestern University scientists have developed a new bioactive material that successfully regenerated high-quality cartilage in the knee joints of a large animal model. Microstructure of the new bioactive material. The fibers are in pink; hyaluronic acid is shown in purple. Image credit: Stupp Group Although it looks like a rubbery goo, the material is actually...
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Immunotherapy for gum disease? Study in mice shows promise
September 30, 2024 by University of Pittsburgh Microparticles containing the immune-modulating compound CCL2. Credit: Julie Kobyra, University of PittsburghTargeting the immune system could prevent or treat periodontal disease (PD), a common but serious disease of the gums, according to new research from the University of Pittsburgh. The study, published in Proceedings of the National Academy...
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Circular peptides in violets may aid in the fight against glioblastoma
September 30, 2024 by Brain Chemistry Labs Wyoming violets. Credit: Dr. Paul Alan Cox, Brain Chemistry LabsGlioblastoma is one of the most serious brain diseases known. More than 45% of brain cancers are gliomas. Only half of glioblastoma patients respond to the FDA-approved chemotherapy temozolomide (TMZ). Even for those patients, the cancer cells quickly evolve...
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Researchers identify new therapeutic approach to preventing cancer from spreading to the brain
October 1, 2024 by McMaster University In a study published in the journal Cell Reports Medicine, researchers Sheila Singh and Jakob Magolan discovered a critical vulnerability in metastatic brain cancer, which they say can be exploited with new drugs to prevent spread. Singh, a professor in McMaster’s Department of Surgery and director of the Center...
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Promising tuberculosis therapy safe for patients with HIV, finds study
October 1, 2024 by Texas Biomedical Research Institute Researchers compare the impacts of cART by itself versus cART plus the IDO inhibitor in lung tissue of nonhuman primates with both TB and SIV. Left: Following just cART, significantly more IDO is detected in pink. Right: With the IDO inhibitor and cART, immune cells recruited to...
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Study finds a reduced risk of serious cardiovascular disease after COVID vaccination
October 1, 2024 by University of Gothenburg People who have been fully vaccinated against COVID-19 have a significantly lower risk of developing more severe cardiovascular conditions linked to COVID-19 infection, according to a nationwide study at the University of Gothenburg. At the same time, some cardiovascular effects are seen after individual doses of the vaccine....