Motortion/iStock via Getty Images Plus Certain medications can affect your dreams — and not always in a good way. Vivid dreams and nightmares can be an unexpected side effect of several medications and supplements, such as melatonin, beta blockers, and antidepressants. And while they don’t happen to everyone, it’s helpful to be aware of some of the...
Does the gut microbiome affect spine health?
(A)–(C) Dynamic lateral lumbar plain radiographs and (D), (E) lumbar T1- and T2-weighted MRI noting spondylolisthesis at L4-L5 and L5-S1 in a 65-year-old female. Credit: JOR SPINE (2024). DOI: 10.1002/jsp2.70005 Are back problems influenced by your gut? Researchers at Rush think there may be a connection. In a paper published in JOR Spine, researchers looked at patients with and without...
Clec14a protein found to play vital role in regulating bone formation and density
New research uncovers how the Clec14a protein in capillary endothelial cells controls bone growth and maturation, revealing a key mechanism in skeletal development. Study: Type-H endothelial cell protein Clec14a orchestrates osteoblast activity during trabecular bone formation and patterning. Image Credit: NTshutterth/Shutterstock.com A recent study published in Communications Biology explored the role of the C-type lectin domain containing 14A (Clec14a),...
Survey finds 25% of adults suspect they have undiagnosed ADHD
Trending social media videos have raised awareness of adult ADHD, but experts warn against self-diagnosis and incorrect treatment Ohio State University Wexner Medical Center video: Survey finds 25% of adults suspect they have undiagnosed ADHD, but only 13% have talked to their doctor about it Credit: The Ohio State University Wexner Medical Center COLUMBUS, Ohio...
Researchers create ‘mini brains’ to model Lewy body dementia and pinpoint treatments
The computational 3D drug-working model depicting the binding interactions between α-SYN aggregates and the drug candidates (D1, D3, D4, and D6) and EGCG at the Tyr39 and Lys43 residues. Credit: Science Advances (2024). DOI: 10.1126/sciadv.adk3700 Lewy body dementia (LBD) is a progressive neurodegenerative disease that shares traits with both Parkinson’s disease and Alzheimer’s disease but can be...
Letter nudges found to increase likelihood of flu vaccination for adults with chronic diseases
For patients aged 18 to 64 years with chronic diseases, electronically delivered letter nudges increase influenza vaccination rates compared with usual care, according to a study published online Oct. 11 in the Journal of the American Medical Association. Niklas Dyrby Johansen, M.D., Ph.D., from Copenhagen University Hospital—Herlev and Gentofte in Denmark, and colleagues examined whether electronically delivered letter-based...
FDA to reconsider removal of Lilly’s GLP-1 drug from shortage list
FDA to reconsider removal of Lilly’s GLP-1 drug from shortage list, a win for compounding pharmaciesShelby LivingstonSenior health tech reporterThe FDA said it will reconsider the removal of Eli Lilly’s GLP-1 drug tirzepatide from its official shortage list, after a trade group representing large compounding pharmacies challenged the move. A federal court in Texas on...
New Gynecology Trials: Could Your Patient Benefit?
Several new studies on gynecologic conditions have started in recent months. Perhaps one of your patients would be interested? Human papillomavirus (HPV) 16–positive, PD-L1–positive, persistent-recurrent or metastatic cervical cancer. Adults with this diagnosis who have progressed on standard first-line therapy of pembrolizumab (Keytruda) plus chemotherapy with/without bevacizumab (Avastin) may be eligible to join a phase 2,...
New molecule can mimic the effects of fasting and exercise
The illustration to the left shows the chemical structure of LaKe. The graphs to the right show how the blood concentrations of lactate and ketones (BHB) change over time in rats that have ingested either LaKe (blue curves) or a control substance (black curves). Both lactate and BHB can be seen to increase significantly in...
Innovative nanoparticle therapy targets fat absorption to combat obesity
(Monday 14 October 2024, Vienna, Austria) Researchers have unveiled a novel approach to tackle obesity by targeting fat absorption in the small intestine. The cutting-edge nanoparticle system, engineered to deliver therapeutic molecules directly to the digestive tract, has shown significant potential to prevent diet-induced obesity.1,2 Presented today at UEG Week 2024, the study focuses on...