Pseudodementia is a set of symptoms that mimic those of dementia, such as problems with speech, memory, or attention. However, it typically has other underlying causes, such as depression. Pseudodementia appears similar to dementia but does not occur due to neurological degeneration. Some people call the condition depressive pseudodementia, as the symptoms often stem from...
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As Eli Lilly, compounders battle over weight loss drugs, patients are caught in the middle
At issue is easy and affordable access to medications By Elaine Chen Oct. 11, 2024 National Biotech Reporter There’s a war brewing over blockbuster weight loss medications — and patients are now getting caught in the crossfire. Last week, the Food and Drug Administration declared an end to the shortage of Eli Lilly’s tirzepatide, sold under the brand name...
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Surgical Center Wins Stunning $421 Million Verdict Against Blue Cross
In a stunning verdict against Blue Cross and Blue Shield of Louisiana, a New Orleans jury has awarded $421 million in damages to a surgery center over the insurer’s alleged failure to fully pay out-of-network charges. Insurance specialists told Medscape Medical News that the September 20 verdict is unusual. If upheld on appeal, one said, it could...
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Worst U.S. whooping cough outbreak in a decade has infected thousands
Whooping cough is spreading nationwide at the highest levels since 2014. There have been more than 16,000 cases this year — more than four times as many compared to the same time last year — and two confirmed deaths. And experts are concerned that the outbreak could worsen in the fall and winter months. “More children are...
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Scientists reveal strong connection between zinc levels and Type 2 Diabetes
The study has significantly elevated science’s comprehension of zinc’s essential role in metabolic processes. (CREDIT: CC BY-SA 3.0)Share this story In an important new study, scientists have found a strong connection between zinc levels in the human body and the risk of developing type 2 diabetes and non-alcoholic fatty liver disease. This research, published in the journal...
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Brain cell connectivity research provides a potential target for anxiety disorders
Synopsis. Credit: The EMBO Journal (2024). DOI: 10.1038/s44318-024-00252-9 Scientists at Université de Montréal and its affiliated Montreal Clinical Research Institute (IRCM) have uncovered unique roles for a protein complex in the structural organization and function of brain cell connectivity, as well as in specific cognitive behaviors. The work by a team led by Hideto Takahashi, director of...
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Cancer drug could be used to save the limbs of peripheral artery disease patients, pre-clinical study suggests
Credit: Science Advances (2024). DOI: 10.1126/sciadv.adn8760 Researchers at the Heart Research Institute (HRI) have made a new discovery, finding an existing drug used to kill tumor cells in cancer patients could also be used to save the limbs of patients with blocked arteries in their legs. A pre-clinical study by HRI’s Center for Peripheral Artery Disease (PAD)...
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‘Phenomenal’ tool sequences DNA and tracks proteins — without cracking cells open
An imaging method reveals various proteins (blue, yellow and magenta) inside the nucleus of a human connective-tissue cell.Credit: Ajay Labade, Zachary Chiang, Caroline Comenho and Jason Buenrostro Researchers are queuing up to try a powerful microscopy technique that can simultaneously sequence an individual cell’s DNA and pinpoint the location of its proteins with high resolution...
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AI scans RNA ‘dark matter’ and uncovers 70,000 new viruses
Newly-discovered viruses live in hydrothermal vents and other extreme environments. Credit: Alexis Rosenfeld/Getty Researchers have used artificial intelligence (AI) to uncover 70,500 viruses previously unknown to science1, many of them weird and nothing like known species. The RNA viruses were identified using metagenomics, in which scientists sample all the genomes present in the environment without having...
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Kinetic analysis of protein and peptide aggregation
Peptide-based pharmaceutical technology necessitates the delivery of therapeutic oligopeptides that are designed in a stable state for efficacious application. Following therapeutic peptide isolation or synthesis, peptides are frequently exposed to HPLC purification, synthetic modification, and preparatory treatments for storage over long periods. During any of these processes, spoilage can happen in the form of aggregation,...