Month: <span>October 2024</span>

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A novel approach to combat fatty liver disease

Peer-Reviewed Publication Ecole Polytechnique Fédérale de Lausanne Metabolic dysfunction-associated steatotic liver disease (MASLD) — previously known as “non-alcoholic fatty liver disease” — affects about 25% of the global population. Its severe form, metabolic dysfunction-associated steatohepatitis (MASH), can lead to liver fibrosis and even liver failure. With only one  approved treatment currently available, finding solutions for...

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Keeping it together: How calcium signals help cells bury their dead neighbors

Researchers discover a calcium-mediated effect that helps preserve the integrity of the sheets of cells lining our bodies and organs. Peer-Reviewed Publication Kyushu University An apoptotic, or dying cell, characterized by its wavy membrane, lies within a cultured sheet of epithelial cells. Credit: Yuma Cho and Junichi Ikenouchi, Kyushu University Fukuoka, Japan—A research team from...

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Ultra-sensitive robotic “finger” can take patient pulses, check for lumps

Peer-Reviewed Publication Researchers at the University of Science and Technology of China have developed a soft robotic “finger” with a sophisticated sense of touch that can perform routine doctor office examinations, including taking a patient’s pulse and checking for abnormal lumps. This work was published October 9 in the Cell Press journal Cell Reports Physical Science....

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Over 160,000 new virus species discovered by AI

Largest discovery of new virus species sheds light on hidden virosphere Peer-Reviewed PublicationUniversity of Sydney Artificial intelligence (AI) has been used to reveal details of a diverse and fundamental branch of life living right under our feet and in every corner of the globe. 161,979 new species of RNA virus have been discovered using a...

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Understanding aging through the lense of gut microbiome

The composition of the gut microbiome exhibits genus-level variations across different age groups. The early-age gut microbiome is shaped by the embryonic environment, type of delivery, and exposure to microbes through breast/formula feeding. During weaning, the microbiome undergoes changes from a simple (less diverse) to a complex (more diverse) microbial mixture and attains stability until...

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Research finds neurons look different in children with autism

Neuronal measurements could provide new insight into diagnosis and therapeutic interventions for autism Peer-Reviewed Publication University of Rochester Medical Center There is new evidence that the cells responsible for communication in the brain may be structured differently in children with autism. Researchers at the Del Monte Institute for Neuroscience at the University of Rochester discovered that in...

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New strategy could turn intravenous medicines into pills

Examples of water-soluble prodrugs. a Orally administered therapeutics that possess a water-soluble promoiety (e.g. phosphate or phosphonooxymethyl group). b Intravenously administered commercial drugs possessing various water-soluble promoieties. Created in BioRender. Smith, M. (2024) BioRender.com/l22c048. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-52793-6 For many people with cancer, intravenous (IV) infusions of chemotherapy are their best chance at a cure. But these infusions can...

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Weight-loss surgery may lower risk of pancreatic cancer in people with obesity

Obesity and type 2 diabetes are risk factors for various malignancies, including pancreatic cancer, which has a high death rate. A new analysis in Diabetes/Metabolism Research and Reviews suggests that weight-loss surgery—also called metabolic-bariatric surgery—may lower the risk of developing pancreatic cancer in people with obesity, especially in those who also have type 2 diabetes. In the systematic review and meta-analysis,...