A blood test, performed when metastatic prostate cancer is first diagnosed, can predict which patients are likely to respond to treatment and survive the longest. It can help providers decide which patients should receive standard treatment versus who might stand to benefit from riskier, more aggressive new drug trials. The research, part of a Phase...
Month: <span>October 2024</span>
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Commonly used arm positions can substantially overestimate blood pressure readings, study finds
Researchers say their study findings underscore the importance of adhering to clinical guidelines calling for firm arm support on a desk or other surface when measuring blood pressure. Credit: Tammy Brady A study led by Johns Hopkins Medicine researchers concludes that commonly used ways of positioning the patient’s arm during blood pressure (BP) screenings can...
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Scientists discover that special immune cells stop metastatic cancer
Metastatic disease—when cancer spreads from the primary tumor to other parts of the body—is the cause of most cancer deaths. While researchers understand how cancer cells escape the primary site to seed new tumors, it’s not well understood why some of these wayward cancer cells spawn new tumors—sometimes decades later—while others do not. Now, a...
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Cancer biologists discover the drug, 5-fluorouracil, acts differently in different types of cancer
Since the 1950s, a chemotherapy drug known as 5-fluorouracil has been used to treat many types of cancer, including blood cancers and cancers of the digestive tract. Doctors have long believed that this drug works by damaging the building blocks of DNA. However, a new study from MIT has found that in cancers of the...
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Uterine cancer rates are increasing: What can you do to protect yourself?
Uterine cancer is the most common type of gynecologic cancer. It’s estimated that about 67,880 new cases will be diagnosed in 2024. Approximately 13,250 people will die from this disease in the U.S. in 2024, according to the National Cancer Institute. Researchers recently reported that while death rates for the most common type of uterine cancer—endometrioid cancer—remained stable, deaths from...
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Six Tips on Coronavirus Testing for Doctors and Patients
In Germany, the activity of acute respiratory diseases is at a higher level than usual for this time of year because of rhinoviruses and SARS-CoV-2, according to the Robert Koch Institute, Germany. If a patient has a fever and cough and feels exhausted, it could be COVID-19. What significance do rapid tests have? And when should...
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Stanford Breakthrough: Reviving Brain Stem Cells To Combat Aging
Most neurons last a lifetime, but new neurons are still produced by neural stem cells. Stanford researchers identified genes, like GLUT4, that could help reactivate neural stem cells in aging brains, offering hope for neuron regeneration. New research hints at ways to generate neurons. Most neurons in the human brain last a lifetime, and for...
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Cilta-cel found highly effective in first real-world study of patients with relapsed or refractory multiple myeloma
Credit: Pixabay/CC0 Public Domain In the first study to report real-world outcomes from ciltacabtagene autoleucel (cilta-cel), a chimeric antigen receptor (CAR)-T therapy for multiple myeloma, patients experienced efficacy and safety results similar to those seen in clinical trials, according to results published in Blood. Of 236 patients who received cilta-cel infusions at 16 U.S. medical centers in 2022,...
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NEW APPROACH MAKES BONE GRAFTS BETTER
Researchers are succeeding in their efforts to build a better bone graft in the lab. Each year, about 2.2 million bone-grafting procedures are performed worldwide. The gold standard of care is autografting, which uses the patient’s own bone for tooth implantation and to repair and reconstruct parts of the mouth, face, and skull. There are drawbacks...
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New molecule can mimic the effects of fasting and exercise
Researchers from AU, Denmark, have developed a molecule that can mimic a major metabolic response to regular and strenuous exercise and fasting by increasing levels of lactate and ketones in the blood, which are associated with several health benefits Peer-Reviewed Publication Aarhus University image: The illustration to the left shows the chemical structure of LaKe....