Cannabis use is becoming increasingly common among people with diabetes. A recent US prevalence study estimated that 9% adults with diabetes used cannabis in the last month, a 33.7% increase between 2021 and 2022. Nearly half (48.9%) of users were younger than 50 years. Cannabis use is also increasing sharply among those aged 65 years or older, many of...
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In situ tumor vaccine with optimized nanoadjuvants and lymph node targeting capacity to treat ovarian cancer and metastases
News Release 25-Sep-2024 Peer-Reviewed PublicationCompuscript Ltd This new article publication from Acta Pharmaceutica Sinica B, discusses the use of in situ tumor vaccine with optimized nanoadjuvants and lymph node targeting capacity to treat ovarian cancer and metastases. Tumor vaccine, a promising modality of tumor immunotherapy, needs to go through the process of tumor antigen generation...
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Measure of body roundness may help to predict risk of cardiovascular disease
News Release 25-Sep-2024 Abdominal body fat could hint at cardiovascular disease risk even when other health factors are not considered, finds new study in Journal of the American Heart Association Peer-Reviewed PublicationAmerican Heart Association Research Highlights: Body roundness index — a measure to reflect abdominal body fat and height that some health care professionals believe...
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Novel regulator of glucose transport in adipose tissue discovered
News Release 25-Sep-2024 Peer-Reviewed PublicationDeutsches Zentrum fuer Diabetesforschung DZD The role of the adapter protein PICALM in the development of Alzheimer’s disease is well documented. Researchers from the German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), the German Center for Diabetes Research (DZD), ETH Zurich and the University of Cambridge have now for the first time...
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Chung-Ang University researchers identify a potential anti-aging drug
News Release 25-Sep-2024 Scientists investigated a drug namely IU1 for mitigating age-related problems in protein quality control systems Peer-Reviewed PublicationChung Ang University Using fruit flies as an animal model, researchers shed light on the synergistic effects of two different mechanisms by which cells destroy faulty proteins that lead to aging. Moreover, by administering a modern...
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CRISPR-Cas13: A new frontier in RNA-editing with revolutionary therapeutic potential
News Release 25-Sep-2024 Researchers reviewed the recent therapeutic developments and upcoming challenges of CRISPR-Cas13, a cutting-edge RNA-editing technology Peer-Reviewed PublicationNanjing Agricultural University The Academy of Science In recent years, the scientific community has made significant strides in the field of gene editing, particularly through the development of the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)...
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Pipeline of new drug treatment for non-alcoholic fatty liver disease/metabolic dysfunction-associated steatotic liver disease
News Release 25-Sep-2024 Peer-Reviewed PublicationXia & He Publishing Inc. ACC, Acetyl-CoA Carboxylase; PPAR, peroxisome proliferator–activated receptor; MPC, mitochondrial pyruvate carrier; THR, thyroid hormone receptor; ASK-1, apoptosis signaling kinase-1; GLP-1R, glucagon-like peptide-1 receptor; GCGR, glucagon receptor; GIPR, glucose-dependent insulinotropic polypeptide receptor; PDE, phosphodiesterase; SGLT, sodium–glucose cotransporter; FXR, farnesoid X receptor; SCD1, stearoyl-CoA desaturase 1; FGFR4/1, fibroblast...
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Now we know why children with Down’s syndrome have higher risk of Leukemia
News Release 25-Sep-2024 Peer-Reviewed PublicationUniversity of Copenhagen – The Faculty of Health and Medical Sciences People with Down’s syndrome face a higher risk of developing Leukemia. Now researchers from the University of Copenhagen and Stanford University explain why, by identifying specific changes in blood cells of people with Down’s syndrome. In the world, one out...
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Bacterial ‘flipping’ allows genes to assume different forms
News Release 25-Sep-2024 A gene can code for multiple bacterial features Peer-Reviewed PublicationStanford Medicine Imagine being one cartwheel away from changing your appearance. One flip, and your brunette locks are platinum blond. That’s not too far from what happens in some prokaryotes, or single-cell organisms, such as bacteria, that undergo something called inversions. A study...
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Researchers identify genetic mutations for rare disorder causing cognitive decline
September 24, 2024 by Mayo Clinic The countries where the disease was reported by 2018 are shown in blue. The countries where the disease was reported between 2018 and 2023 are shown in yellow. The newly reported countries are shown in red. Credit: Neurology Genetics (2024). DOI: 10.1212/NXG.0000000000200187A rare cause of hereditary cognitive decline known...