by British Medical Journal Credit: Pixabay/CC0 Public DomainThere seems to be a J-shaped curve between dietary thiamine (vitamin B1) and worsening mental acuity among cognitively healthy older people, suggests research published in the open-access journal General Psychiatry. The sweet spot seems to be a daily intake of 0.68 mg, below which there is relatively little impact....
Year: <span>2024</span>
Playing video games may improve attention and memory, research finds
by Lero Depiction of two example sequences containing two correct moves (top) and an incorrect move and correction (bottom) for the Groton Maze Task. Each time a correct move is made, the corresponding tile flashes green. When an incorrect move is made, the corresponding tile flashes red. The right-most image highlights the 28 moves and...
Researchers pioneer novel stem cell therapy for diabetic wound healing
by TranSpread Hypoxia facilitates exosome production and release from BMSCs. (a) Transmission electron microscopy (TEM) revealed the morphology of noBMSC-Exos and hyBMSC-Exos (scale bar: 100 nm). (b) The size distribution of noBMSC-Exos and hyBMSC-Exos was examined using nanoparticle tracking analysis (NTA). (c and d) Western blotting analysis for exosome surface marker proteins, including CD9, CD63,...
Modifying brain molecule relaxin-3 can potentially reduce side effects in treating anxiety, depression and more
by National University of Singapore An illustration of computer-modeled structures of complexes formed between RXFP3 and relaxin-3 or relaxin-3 B-chain stapled peptides. Credit: NUS Yong Loo Lin School of Medicine and University of Colombo, Sri LankaDrugs that treat conditions like depression and anxiety often come with varying side effects, as they regulate various functions within the...
Blocking key protein may halt progression of Alzheimer’s disease
by CU Anschutz Medical Campus Credit: CC0 Public DomainResearchers at the University of Colorado Anschutz Medical Campus have found that inhibiting a key protein can stop the destruction of synapses and dendritic spines commonly seen in Alzheimer’s disease. The study, whose first author is Tyler Martinez, a student in the Pharmacology and Molecular Medicine Ph.D. program...
Age-related changes in fibroblast cells promote pancreatic cancer growth and spread
by Johns Hopkins University School of Medicine Axial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainOlder people may be at greater risk of developing pancreatic cancer and have poorer prognoses because of age-related changes in cells in the pancreas called fibroblasts, according to research led by investigators from the Johns...
This Small Wearable Device Reduces Parkinson’s Symptoms
People with Parkinson’s have fewer tremors when they receive rhythmic physical stimulation—so a UK startup has created a coin-sized vibrating device to help patients move more easily. PHOTOGRAPH: CHARCO NEUROTECH IN 2015, LUCY Jung was a young industrial designer working on assistive devices for stroke victims, people with multiple sclerosis, and those with other conditions...
Scientists discover new target for reversible, non-hormonal male birth control
by Salk Institute Sperm, pictured inside each round cell, were not generated while mice took the HDAC inhibitor drug (top right), but after 60 days off the drug, spermatogenesis was recovered (bottom right). The left column shows sperm at the same time points in a mouse that did not receive the drug. Credit: Salk InstituteSurveys show...
Terahertz biosensor detects skin cancer with remarkable accuracy, advancing new era of early detection
by Queen Mary, University of London Credit: IEEE Transactions on Biomedical Engineering (2024). DOI: 10.1109/TBME.2024.3364386Researchers have developed a revolutionary biosensor using terahertz (THz) waves that can detect skin cancer with exceptional sensitivity, potentially paving the way for earlier and easier diagnoses. Published in IEEE Transactions on Biomedical Engineering, the study presents a significant advancement in early...
Little-known devices restore vision to people who can’t be helped by regular glasses
by Katy Read, Star Tribune Credit: Unsplash/CC0 Public DomainDick Bramer, 76, likes to watch birds flock outside the window of his home in Scandia. But for two years he couldn’t see them well enough to identify the various species. In July 2021 Bramer suffered what doctors diagnosed as an ocular stroke (they said a small...