by Elana Gotkine For adults with complicated urinary tract infection (UTI), including acute pyelonephritis, cefepime-taniborbactam is superior to meropenem, according to a study published in the Feb. 15 issue of the New England Journal of Medicine.Florian M. Wagenlehner, M.D., from Justus Liebig University in Giessen, Germany, and colleagues conducted a phase 3 randomized trial involving...
by University of Barcelona Credit: Journal of Clinical Investigation Insight (2024). DOI: 10.1172/jci.insight.163359. https://insight.jci.org/articles/view/163359Parkinson’s disease is one of the most common diseases affecting the motor and nervous system. It has no treatment yet, and the pathology causes a deterioration of motor skills due to dopaminergic neuronal death, the neurons that synthesize dopamine, which is a brain...
by Alexander Easton, The Conversation Credit: Ivan Samkov from PexelsForgetting in our day to day lives may feel annoying or, as we get older, a little frightening. But it is an entirely normal part of memory—enabling us to move on or make space for new information. In fact, our memories aren’t as reliable as we may...
by Christopher P. Holstege, The Conversation Credit: Pixabay/CC0 Public DomainTwo deaths in Boulder County, Colorado, in 2023 are the latest in the U.S. to be blamed on the powerful class of synthetic opioids called nitazenes. Most health systems cannot detect nitazenes, so the exact number of overdoses is unknown, but they’re implicated in more than 200...
Lucy Hicks A new diagnostic tool can effectively discriminate different rheumatologic conditions and could potentially aid in the diagnosis of early inflammatory arthritis. The algorithm — called Genetic Probability tool (G-PROB) — uses genetic information to calculate the probability of certain diseases. “At such an early stage of disease, it’s not always easy to determine...
by Impact Journals LLC Effect of GV1001 on aging, telomere maintenance, and long-term memory confirmed via bioinformatics analysis. Credit: Aging (2024). DOI: 10.18632/aging.205489A new research paper titled “GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects” has been published in Aging. GV1001, which mimics the activity of human telomerase reverse transcriptase,...
by Mike Stobbe This undated file photo provided by the U.S. Centers for Disease Control and Prevention (CDC) shows a blacklegged tick, also known as a deer tick, a carrier of Lyme disease. U.S. Lyme disease cases jumped nearly 70% in 2022, according to a report released by the Centers for Disease Control and Prevention...
by Mike Stobbe A man prepares to smoke fentanyl on a park bench in downtown Portland, Ore., on Thursday, May 18, 2023. Smoking has surpassed injecting as the most common way of taking drugs in U.S. overdose deaths, according to a study published by the Centers for Disease Control and Prevention on Thursday, Feb. 15,...
by Pusan National University The study associating periodontitis (PD) and diabetes mellitus (DM) using single-cell RNA analysis offers the first immunological explanation, revealing altered immune cell function and suggesting PD as a potential precursor to DM through the RESISTIN pathway. Credit: Yun Hak Kim from Pusan National UniversityPeriodontitis (PD) is a common complication in individuals with...
by Aarhus University Ratings of sensations in visual analog scales (VAS), and corresponding areas under the curve (AUC), for satiety (A & B), fullness (C & D), satisfaction (E & F), hunger (G & H), desire to eat (J & K), and prospective eating (L & M) at specific time points throughout 3 separate experimental days...
