by Stanford University Medical Center Credit: RDNE Stock project from PexelsFor military veterans, many of the deepest wounds of war are invisible: Traumatic brain injuries resulting from head trauma or blast explosions are a leading cause of post-traumatic stress disorder, anxiety, depression and suicide among veterans. Few treatments have been effective at diminishing the long-term effects...
Year: <span>2024</span>
Discovery unveils immune system’s guardian: Ikaros
by Monash University Credit: Pixabay/CC0 Public DomainIn a scientific breakthrough that aids our understanding of the internal wiring of immune cells, researchers at Monash University in Australia have cracked the code behind Ikaros, an essential protein for immune cell development and protection against pathogens and cancer. This disruptive research, led by the eminent Professor Nicholas Huntington...
Study shows liraglutide results in increased insulin sensitivity independent of weight loss
by Vanderbilt University Medical Center Graphical abstract. Credit: Diabetes (2023). DOI: 10.2337/db23-0356A recent study published in the journal Diabetes demonstrates that a glucagon-like peptide-1 receptor (GLP-1R) agonist, a member of a class of medication used to treat type 2 diabetes and obesity, can lead to a rapid improvement in insulin sensitivity. Insulin sensitivity is how responsive...
Sudden hearing loss study: High-dose therapy does not lead to better outcomes than the standard treatment
by Martin Luther University Halle-Wittenberg Credit: Unsplash/CC0 Public DomainIn the case of sudden hearing loss, high-dose therapy with common medications is not more effective than standard treatment but is associated with a higher risk of side effects. This is the main result of a large-scale Germany-wide randomized controlled trial with more than 300 patients led by...
The Way the Brain Learns is Different from the Way that Artificial Intelligence Systems Learn
Researchers from the MRC Brain Network Dynamics Unit and Oxford University’s Department of Computer Science have set out a new principle to explain how the brain adjusts connections between neurons during learning.This new insight may guide further research on learning in brain networks and may inspire faster and more robust learning algorithms in artificial intelligence....
3D Organization of DNA Controls Cell Identity Programs
In a complex called chromatin, long strands of DNA in cells’ nuclei are tightly wrapped around a scaffolding of proteins, like a rolled-up ball of yarn. DNA – artistic interpretation.DNA – artistic interpretation. Image credit: Alius Noreika, created with Bing Image CreatorA new study by Weill Cornell Medicine investigators reveals that beyond providing a convenient...
Study Demonstrates Potency of Synthetic Antibiotic Against Serious Chronic Infections
A new synthetic antibiotic developed by University of Liverpool researchers is shown to be more effective than established drugs against ‘superbugs’ such as MRSA, a new study shows.New synthetic antibiotic in action – artistic interpretation. Image credit: University of Liverpool The study demonstrates the potent activity of the antibiotic, teixobactin, against bacterial biofilms. Biofilms are...
Researchers explore changes to microbiome following weight-loss surgery
by Jim Oldfield, University of Toronto Graphical abstract. Credit: Cell Reports Medicine (2023). DOI: 10.1016/j.xcrm.2023.101051Researchers at the University of Toronto and its partner hospitals are finding that changes in gut microbiota after bariatric surgery can directly improve metabolism, independent of food intake, weight loss and other metabolic factors. Their ongoing work—including a study published in the...
HIV vaccine takes step forward with confirmation of neutralizing antibodies
by Sarah Avery, Duke University Graphical abstract. Credit: Cell (2024). DOI: 10.1016/j.cell.2023.12.002The path to a successful HIV vaccine depends on a critical first step—activating specific immune cells that induce broadly neutralizing antibodies. Reporting Jan. 4 in the journal Cell, a research team led by the Duke Human Vaccine Institute has achieved that requisite initial step in...
Bacterial enzyme research paves the way for acne vaccine
by Sara Bock, University of California Comparison of HylA and HylB with bacterial and animal Hyl. Credit: Nature Communications (2023). DOI: 10.1038/s41467-023-43833-8In a groundbreaking development in the field of anti-acne therapies, a team of researchers at University of California San Diego School of Medicine has created an acne vaccine that successfully reduces inflammation in a...